Table 4 Comparison of FLC and... | American Society of Hematology

Table 4

Comparison of FLC and paraprotein methods predicting ECOG overall objective response status*

FLC response	No. of patients	2-month FLC response			2-month paraprotein response			P†
FLC response	No. of patients	Sensitivity %	Specificity %	Risk	Sensitivity %	Specificity %	Risk	P†
Overall population	181	69	73	0.30	34	98	0.48	<.001
Patients with iFLC more than 10 mg/dL	120	83	67	0.24	36	100	0.43	.001
Patients with abnormal rFLC and dFLC 5 mg/dL or more	139	77	69	0.26	34	100	0.45	<.001

FLC response	No. of patients	2-month FLC response			2-month paraprotein response			P†
FLC response	No. of patients	Sensitivity %	Specificity %	Risk	Sensitivity %	Specificity %	Risk	P†
Overall population	181	69	73	0.30	34	98	0.48	<.001
Patients with iFLC more than 10 mg/dL	120	83	67	0.24	36	100	0.43	.001
Patients with abnormal rFLC and dFLC 5 mg/dL or more	139	77	69	0.26	34	100	0.45	<.001

Among patients with both paraprotein and FLC data after 2 months of therapy.

Risk comparison.