Table 2

Propeptide and VWF antigen levels and activity of ADAMTS13

LAC positive due to anti–β2GPI antibodiesLAC positive due to antiprothrombin antibodiesLAC-negative SLE patients
VWF antigen, μg/mL 23.4 ± 9.4 18.3 ± 4.5 22.1 ± 9.1 
VWF propeptide, μg/mL 0.17 ± 0.10 0.13 ± 0.05 0.16 ± 0.14 
Propeptide/mature VWF, mol/mol 0.09 ± 0.03 0.09 ± 0.03 0.08 ± 0.02 
ADAMTS13 activity, % 81.7 ± 28.5 71.7 ± 31.1 66.5 ± 20.8 
LAC positive due to anti–β2GPI antibodiesLAC positive due to antiprothrombin antibodiesLAC-negative SLE patients
VWF antigen, μg/mL 23.4 ± 9.4 18.3 ± 4.5 22.1 ± 9.1 
VWF propeptide, μg/mL 0.17 ± 0.10 0.13 ± 0.05 0.16 ± 0.14 
Propeptide/mature VWF, mol/mol 0.09 ± 0.03 0.09 ± 0.03 0.08 ± 0.02 
ADAMTS13 activity, % 81.7 ± 28.5 71.7 ± 31.1 66.5 ± 20.8 

All data represent mean (± SD), n = 10. Normal ranges are as follows: VWF antigen, 6.1-14.2 μg/mL; VWF propeptide, 0.6-1.6 μg/mL; propeptide/mature VWF ratio, 0.04-0.21; and ADAMTS13 activity, 61%-142 %.

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