Table 4

Cox regression analysis of the relapse risk by quantitative BM PCR, histologic subtype, and clinical risk features of 74 analyzed patients

VariableRelative risk of relapse95% confidence intervalP
BM NPM-ALK more than 10 NCNs 4.74 1.57-14.3 .006 
Histologic subtype: not common 3.00 0.84-10.71 .09 
Clinical risk features* 1.67 0.53-5.23 .38 
VariableRelative risk of relapse95% confidence intervalP
BM NPM-ALK more than 10 NCNs 4.74 1.57-14.3 .006 
Histologic subtype: not common 3.00 0.84-10.71 .09 
Clinical risk features* 1.67 0.53-5.23 .38 

BM indicates bone marrow; NCN, copies NPM-ALK/104 copies ABL.

*

Clinical risk features: involvement of skin, mediastinum, liver, spleen, or lung.