Presence of antibody to bovine apoB-100 in HIV patients receiving identical twin lymphocytes cultured in FCS-containing media
Infusion no. . | Time after infusion, wk . | Presence of bovine* ApoB-100 antibody . |
---|---|---|
Patient A | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | − |
3 | 2 | ++ |
Patient B | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | +− |
3 | 4 | + |
Patient C | ||
Preinfusion | NA | − |
2 | 2 | − |
3 | 4 | ++ |
4 | 4 | ++++ |
Patient D | ||
Preinfusion | NA | − |
4 | 4 | ++++ |
Patient E | ||
Preinfusion | NA | − |
1 | 1 | − |
1 | 3 | − |
2 | 1 | − |
2 | 3 | + |
3 | 2 | +++ |
Patient F | ||
Preinfusion | NA | − |
1 | 1 | − |
1 | 3 | − |
2 | 1 | − |
2 | 3 | + |
3 | 2 | ++ |
Patient G | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | − |
3 | 2 | +− |
Patient H | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | − |
3 | 6 | +− |
Patient I | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | NA | − |
2 | 2 | + |
Infusion no. . | Time after infusion, wk . | Presence of bovine* ApoB-100 antibody . |
---|---|---|
Patient A | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | − |
3 | 2 | ++ |
Patient B | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | +− |
3 | 4 | + |
Patient C | ||
Preinfusion | NA | − |
2 | 2 | − |
3 | 4 | ++ |
4 | 4 | ++++ |
Patient D | ||
Preinfusion | NA | − |
4 | 4 | ++++ |
Patient E | ||
Preinfusion | NA | − |
1 | 1 | − |
1 | 3 | − |
2 | 1 | − |
2 | 3 | + |
3 | 2 | +++ |
Patient F | ||
Preinfusion | NA | − |
1 | 1 | − |
1 | 3 | − |
2 | 1 | − |
2 | 3 | + |
3 | 2 | ++ |
Patient G | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | − |
3 | 2 | +− |
Patient H | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | 2 | − |
3 | 6 | +− |
Patient I | ||
Preinfusion | NA | − |
1 | 2 | − |
2 | NA | − |
2 | 2 | + |
FCS lysate was immunoprecipitated with 10 μL of each serum and the precipitants analyzed by SDS-PAGE. Nine of 17 patients had a response to bovine apoB-100. Eight had a negative response. This table shows patients who were positive.
Reference band intensity: — indicates ≤ 0%; +/−, 0%-20%; +, 20%-60%; ++, 60%-100%; +++, 100%-140%; ++++, >140%.