Cytokine and chemokine serum levels in patients at the time of aGVHD and in matched control group
| Cytokine/chemokine . | GVHD . | No GVHD . |
|---|---|---|
| IL-1β | 2 (2-6) | 2 (2-54) |
| IL-2 | 2 (2-4) | 2 (2) |
| IL-4 | 0.5 (0.5) | 0.5 (0.5) |
| IL-6 | 0.5 (0.5-78) | 3.5 (0.5-648) |
| IL-10 | 1.5 (1.5-10) | 1.5 (1.5-3) |
| IL-12 | 0.5 (0.5-8) | 0.5 (0.5-1) |
| TNF-α | 1.5 (1.5-14) | 1.5 (1.5-105) |
| IFN-γ | 0.5 (0.5-12) | 0.5 (0.5-5) |
| GM-CSF | 0.5 (0.5-4) | 0.5 (0.5) |
| CXCL8 | 71.5 (3-907) | 174 (0.5-434) |
| CXCL9 | 1625 (100-10 000) | 1133 (100-10 000) |
| CXCL10 | 582 (27-3728)* | 197 (41-775) |
| CXCL11 | 21 (1.5-252) | 12.6 (1.5-172) |
| CCL2 | 89 (7-638) | 129 (37-410) |
| CCL3 | 45 (45-2371) | 45 (45-7133) |
| CCL5 | 432 (227-2126) | 341 (262-517) |
| CCL11 | 9 (9-90) | 9 (9) |
| Cytokine/chemokine . | GVHD . | No GVHD . |
|---|---|---|
| IL-1β | 2 (2-6) | 2 (2-54) |
| IL-2 | 2 (2-4) | 2 (2) |
| IL-4 | 0.5 (0.5) | 0.5 (0.5) |
| IL-6 | 0.5 (0.5-78) | 3.5 (0.5-648) |
| IL-10 | 1.5 (1.5-10) | 1.5 (1.5-3) |
| IL-12 | 0.5 (0.5-8) | 0.5 (0.5-1) |
| TNF-α | 1.5 (1.5-14) | 1.5 (1.5-105) |
| IFN-γ | 0.5 (0.5-12) | 0.5 (0.5-5) |
| GM-CSF | 0.5 (0.5-4) | 0.5 (0.5) |
| CXCL8 | 71.5 (3-907) | 174 (0.5-434) |
| CXCL9 | 1625 (100-10 000) | 1133 (100-10 000) |
| CXCL10 | 582 (27-3728)* | 197 (41-775) |
| CXCL11 | 21 (1.5-252) | 12.6 (1.5-172) |
| CCL2 | 89 (7-638) | 129 (37-410) |
| CCL3 | 45 (45-2371) | 45 (45-7133) |
| CCL5 | 432 (227-2126) | 341 (262-517) |
| CCL11 | 9 (9-90) | 9 (9) |
Data are cytokine and chemokine median values, pg/mL (range).
P < .01, according to Mann-Whitney U test.