SKY and MYC expression of TCL1-tg B-cell lymphomas
Tumor . | MMHCC . | Translocation . | No. metaphases (no. abnormal metaphases) . | Trisomy 15 . | MYC . |
---|---|---|---|---|---|
K1 | DLBCL | ND | ND | ND | 0.7 |
K2 | BLL | ND | ND | ND | 1.2 |
K7 | BLL | T(11;17) | 16 (16) | + | 3.2 |
K9 | DLBCL | None | 11 (0) | − | 2.2 |
K10 | BLL | T(2;5),T(X;7),T(7;9),T(9;X) | 9 (8) | + | 1.8 |
K14 | DLBCL | ND | ND | ND | 1.0 |
K15 | BLL | ND | ND | ND | 1.8 |
K18 | BLL | T(5;12) | 14 (12) | + | 2.0 |
P3 | BLL | der(5),T(2;5) | 8 (8) | + | 3.1 |
WT | NA | ND | ND | ND | ∼0 |
Tumor . | MMHCC . | Translocation . | No. metaphases (no. abnormal metaphases) . | Trisomy 15 . | MYC . |
---|---|---|---|---|---|
K1 | DLBCL | ND | ND | ND | 0.7 |
K2 | BLL | ND | ND | ND | 1.2 |
K7 | BLL | T(11;17) | 16 (16) | + | 3.2 |
K9 | DLBCL | None | 11 (0) | − | 2.2 |
K10 | BLL | T(2;5),T(X;7),T(7;9),T(9;X) | 9 (8) | + | 1.8 |
K14 | DLBCL | ND | ND | ND | 1.0 |
K15 | BLL | ND | ND | ND | 1.8 |
K18 | BLL | T(5;12) | 14 (12) | + | 2.0 |
P3 | BLL | der(5),T(2;5) | 8 (8) | + | 3.1 |
WT | NA | ND | ND | ND | ∼0 |
NA indicates not applicable; ND, not done.
Tumors were classified using MMHCC criteria.12,25 All translocations were reciprocal. MYC protein expression levels are listed as ratios to sample K14, set at 1.0.