Table 1.

SKY and MYC expression of TCL1-tg B-cell lymphomas


Tumor

MMHCC

Translocation

No. metaphases (no. abnormal metaphases)

Trisomy 15

MYC
K1   DLBCL   ND   ND   ND   0.7  
K2   BLL   ND   ND   ND   1.2  
K7   BLL   T(11;17)   16 (16)   +   3.2  
K9   DLBCL   None   11 (0)   −   2.2  
K10   BLL   T(2;5),T(X;7),T(7;9),T(9;X)   9 (8)   +   1.8  
K14   DLBCL   ND   ND   ND   1.0  
K15   BLL   ND   ND   ND   1.8  
K18   BLL   T(5;12)   14 (12)   +   2.0  
P3   BLL   der(5),T(2;5)   8 (8)   +   3.1  
WT
 
NA
 
ND
 
ND
 
ND
 
∼0
 

Tumor

MMHCC

Translocation

No. metaphases (no. abnormal metaphases)

Trisomy 15

MYC
K1   DLBCL   ND   ND   ND   0.7  
K2   BLL   ND   ND   ND   1.2  
K7   BLL   T(11;17)   16 (16)   +   3.2  
K9   DLBCL   None   11 (0)   −   2.2  
K10   BLL   T(2;5),T(X;7),T(7;9),T(9;X)   9 (8)   +   1.8  
K14   DLBCL   ND   ND   ND   1.0  
K15   BLL   ND   ND   ND   1.8  
K18   BLL   T(5;12)   14 (12)   +   2.0  
P3   BLL   der(5),T(2;5)   8 (8)   +   3.1  
WT
 
NA
 
ND
 
ND
 
ND
 
∼0
 

NA indicates not applicable; ND, not done.

Tumors were classified using MMHCC criteria.12,25  All translocations were reciprocal. MYC protein expression levels are listed as ratios to sample K14, set at 1.0.

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