Expression of NF-κB-dependent genes in moDCs adult (Ad) and neonatal (NB)
| Gene description . | Symbol . | Ad, basal, mean ± SEM . | Adults, LPS, mean ± SEM . | NB, basal, mean ± SEM . | NB, LPS, mean ± SEM . | Ad LPS vs NB LPS, fold . |
|---|---|---|---|---|---|---|
| Chemokine (C-C motif) ligand 2 | CCL2 | 216 ± 110 | 3057 ± 536 | 1282 ± 364 | 6994 ± 862 | 0.4 |
| Chemokine (C-C motif) ligand 3 | CCL3 | 515 ± 168 | 5084 ± 419 | 361 ± 139 | 5630 ± 757 | 0.9 |
| Chemokine (C-C motif) ligand 4 | CCL4 | 599 ± 141 | 7644 ± 672 | 366 ± 132 | 7327 ± 930 | 1.0 |
| Intercellular adhesion molecule 1 (CD54) | ICAM1 | 539 ± 137 | 1732 ± 128 | 544 ± 110 | 1779 ± 145 | 1.0 |
| Interleukin 12B | IL12B | 14 ± 1 | 1857 ± 359 | 15 ± 0.3 | 1074 ± 411 | 1.7 |
| Interleukin 1 α | IL1A | 48 ± 2 | 1729 ± 684 | 95 ± 36 | 2444 ± 591 | 0.7 |
| Interleukin 1 β | IL1B | 251 ± 94 | 7787 ± 1639 | 174 ± 30 | 9972 ± 603 | 0.8 |
| Interleukin 6 | IL6 | 50 ± 4 | 3802 ± 1171 | 52 ± 10 | 2400 ± 185 | 1.6 |
| Interleukin 8 | IL8 | 277 ± 32 | 6141 ± 912 | 1637 ± 995 | 8623 ± 979 | 0.7 |
| IκBα | NFKB1A | 1698 ± 257 | 6672 ± 703 | 928 ± 179 | 3617 ± 139 | 1.8 |
| Prostaglandin-endoperoxide synthase 2 | PTGS2 | 16 ± 1 | 1237 ± 428 | 16 ± 2 | 998 ± 307 | 1.2 |
| Tumor necrosis factor α | TNF | 147 ± 45 | 1870 ± 320 | 77 ± 17 | 1175 ± 452 | 1.6 |
| Gene description . | Symbol . | Ad, basal, mean ± SEM . | Adults, LPS, mean ± SEM . | NB, basal, mean ± SEM . | NB, LPS, mean ± SEM . | Ad LPS vs NB LPS, fold . |
|---|---|---|---|---|---|---|
| Chemokine (C-C motif) ligand 2 | CCL2 | 216 ± 110 | 3057 ± 536 | 1282 ± 364 | 6994 ± 862 | 0.4 |
| Chemokine (C-C motif) ligand 3 | CCL3 | 515 ± 168 | 5084 ± 419 | 361 ± 139 | 5630 ± 757 | 0.9 |
| Chemokine (C-C motif) ligand 4 | CCL4 | 599 ± 141 | 7644 ± 672 | 366 ± 132 | 7327 ± 930 | 1.0 |
| Intercellular adhesion molecule 1 (CD54) | ICAM1 | 539 ± 137 | 1732 ± 128 | 544 ± 110 | 1779 ± 145 | 1.0 |
| Interleukin 12B | IL12B | 14 ± 1 | 1857 ± 359 | 15 ± 0.3 | 1074 ± 411 | 1.7 |
| Interleukin 1 α | IL1A | 48 ± 2 | 1729 ± 684 | 95 ± 36 | 2444 ± 591 | 0.7 |
| Interleukin 1 β | IL1B | 251 ± 94 | 7787 ± 1639 | 174 ± 30 | 9972 ± 603 | 0.8 |
| Interleukin 6 | IL6 | 50 ± 4 | 3802 ± 1171 | 52 ± 10 | 2400 ± 185 | 1.6 |
| Interleukin 8 | IL8 | 277 ± 32 | 6141 ± 912 | 1637 ± 995 | 8623 ± 979 | 0.7 |
| IκBα | NFKB1A | 1698 ± 257 | 6672 ± 703 | 928 ± 179 | 3617 ± 139 | 1.8 |
| Prostaglandin-endoperoxide synthase 2 | PTGS2 | 16 ± 1 | 1237 ± 428 | 16 ± 2 | 998 ± 307 | 1.2 |
| Tumor necrosis factor α | TNF | 147 ± 45 | 1870 ± 320 | 77 ± 17 | 1175 ± 452 | 1.6 |