Table 1 Distribution of leukocytes Organ... | American Society of Hematology

Table 1

Distribution of leukocytes

Organ	Cell number (× 10⁵)
	Mononuclear cells		CD3⁺ T-cells		B220⁺ B-cells
	WT	α₄-G/A^GFFKR	WT	α₄-G/A^GFFKR	WT	α₄-G/A^GFFKR
BM*	260 ± 60	290 ± 60	2.7 ± 0.5	3.5 ± 0.1	59 ± 0.8	66 ± 2.3
Spleen*	650 ± 200	630 ± 120	160 ± 7	210 ± 50	370 ± 35	320 ± 5
Thymus*	850 ± 340	820 ± 270	180 ± 80	250 ± 49	ND	ND
PLN†	9.8 ± 1.8	12 ± 2.1	4.4 ± 0.8	5.4 ± 1.0	5.4 ± 1.0	6.6 ± 1.1
MLN†	6.0 ± 3.3	9.9 ± 5.2	4.1 ± 1.7	5.6 ± 3.4	2.6 ± 1.1	3.8 ± 1.7
IEL*	22 ± 5.2	7.0 ± 1.4‡	20 ± 4.2	6.0 ± 1.4‡	ND	ND
PP†	4.4 ± 0.8	1.3 ± 0.7‡	0.63 ± 0.2	0.11 ± 0.1‡	3.5 ± 0.5	1.1 ± 0.7‡

Organ	Cell number (× 10⁵)
	Mononuclear cells		CD3⁺ T-cells		B220⁺ B-cells
	WT	α₄-G/A^GFFKR	WT	α₄-G/A^GFFKR	WT	α₄-G/A^GFFKR
BM*	260 ± 60	290 ± 60	2.7 ± 0.5	3.5 ± 0.1	59 ± 0.8	66 ± 2.3
Spleen*	650 ± 200	630 ± 120	160 ± 7	210 ± 50	370 ± 35	320 ± 5
Thymus*	850 ± 340	820 ± 270	180 ± 80	250 ± 49	ND	ND
PLN†	9.8 ± 1.8	12 ± 2.1	4.4 ± 0.8	5.4 ± 1.0	5.4 ± 1.0	6.6 ± 1.1
MLN†	6.0 ± 3.3	9.9 ± 5.2	4.1 ± 1.7	5.6 ± 3.4	2.6 ± 1.1	3.8 ± 1.7
IEL*	22 ± 5.2	7.0 ± 1.4‡	20 ± 4.2	6.0 ± 1.4‡	ND	ND
PP†	4.4 ± 0.8	1.3 ± 0.7‡	0.63 ± 0.2	0.11 ± 0.1‡	3.5 ± 0.5	1.1 ± 0.7‡

BM indicates bone marrow; PLN, peripheral lymph node; MLN, mesenteric lymph node; IEL, intraepithelial lymphocyte; PP, Peyer patch; and ND, not detected.

Numbers of cells per mouse.

†

Numbers of cells per node.

‡

P < .01 versus WT.

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