Table 2

Baseline laboratory descriptive features

p16 status
Combined
UnmethylatedMethylated
Median age, y 62.5 63.8 62.9 
Serum heavy chain, if serum protein present, %    
    IgG 74.7 65.8 71.6 
    IgA 24.9 32.5 27.5 
    IgM 0.4 0.0 0.3 
    IgD 0.0 1.7 0.58 
Serum light chain type, if serum M protein present, %    
    Kappa 69.6 64.1 67.7 
    Lambda 30.4 35.8 32.3 
Urine light chain type, if urine M protein present, %    
    Kappa 67.6 68.5 67.9 
    Lambda 32.4 31.4 32.1 
Creatinine level, mg/dL 1.2 1.2 1.2 
Calcium level, mg/dL 9.4 9.6 9.4 
PCLI, % PCs 0.4 0.6 0.4 
Hemoglobin level, g/L 109 105 108 
β2-Microglobulin level, mg/dL 3.4 3.6 3.4 
Bone marrow PC, % 25.0 25.0 25.0 
Peripheral blood PC, % 
p16 status
Combined
UnmethylatedMethylated
Median age, y 62.5 63.8 62.9 
Serum heavy chain, if serum protein present, %    
    IgG 74.7 65.8 71.6 
    IgA 24.9 32.5 27.5 
    IgM 0.4 0.0 0.3 
    IgD 0.0 1.7 0.58 
Serum light chain type, if serum M protein present, %    
    Kappa 69.6 64.1 67.7 
    Lambda 30.4 35.8 32.3 
Urine light chain type, if urine M protein present, %    
    Kappa 67.6 68.5 67.9 
    Lambda 32.4 31.4 32.1 
Creatinine level, mg/dL 1.2 1.2 1.2 
Calcium level, mg/dL 9.4 9.6 9.4 
PCLI, % PCs 0.4 0.6 0.4 
Hemoglobin level, g/L 109 105 108 
β2-Microglobulin level, mg/dL 3.4 3.6 3.4 
Bone marrow PC, % 25.0 25.0 25.0 
Peripheral blood PC, % 

Conversion factors are as follows: to convert β2-microglobulin to nM/L, × 85; to convert calcium to mmol/L, × 0.25; and to convert creatinine to μM/L, × 88.4.

PCLI indicates plasma cell labeling index.

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