Table 1 Frequency of progenitor cells... | American Society of Hematology

Table 1

Frequency of progenitor cells prospectively isolated from marrow and spleen of Gata1^low and wild-type littermates

	GMPs, %	CMPs, %	MEPs, %	MCPs, %
Wild type
BM	36.7 ± 3.4	34.1 ± 0.7	20.8 ± 0.7	4.0 ± 0.2
Spleen	BD	BD	BD	BD
GATA-1^low
BM	32.8 ± 3.9	35.5 ± 3.7	15.5 ± 1.5*	< 0.1*
Spleen	18.3 ± 6.3	26.6 ± 3.8	34.1 ± 6.0	< 0.1*

	GMPs, %	CMPs, %	MEPs, %	MCPs, %
Wild type
BM	36.7 ± 3.4	34.1 ± 0.7	20.8 ± 0.7	4.0 ± 0.2
Spleen	BD	BD	BD	BD
GATA-1^low
BM	32.8 ± 3.9	35.5 ± 3.7	15.5 ± 1.5*	< 0.1*
Spleen	18.3 ± 6.3	26.6 ± 3.8	34.1 ± 6.0	< 0.1*

GMPs are defined as CD16/CD32⁺/CD34⁺; CMPs, as CD16/CD32⁻/CD34⁺; MEPs, as CD16/CD32⁻/CD34⁻; and MCPs, as T1/ST2⁺. All the cells are c-Kit⁺. Results are presented as the mean ± SD of at least 3 experiments per group of mice.

BM indicates bone marrow; BD, below detectable levels.

Values statistically different (P < .05) from those observed in wild-type littermates.

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