Table 1

Development of skin GVHD in [H2-Ab1−/− → C3H] mice

PathologyScore
Thickened dermis 1.6 ± 0.5* 
Fat loss 1.9 ± 0.2* 
Epidermis atrophy 0.8 ± 0.3* 
Follicle loss 0.9 ± 0.5* 
Inflammation 0.0 ± 0.0 
Total 5.3 ± 1.0* 
PathologyScore
Thickened dermis 1.6 ± 0.5* 
Fat loss 1.9 ± 0.2* 
Epidermis atrophy 0.8 ± 0.3* 
Follicle loss 0.9 ± 0.5* 
Inflammation 0.0 ± 0.0 
Total 5.3 ± 1.0* 

The skin was analyzed using the histopathologic scoring system described in “Assessment of GVHD” 10 weeks after BMT. For [H2-Ab1−/− → C3H] mice, n = 16. The data are expressed as the mean ± SD. Scores were 0.0 ± 0.0 for all 15 [WT → C3H] mice.

*

P < .01.

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