Table 5.

Characteristics of clonal repertoire in studied patients


Diagnosis

No. clones per patient

Average clone, %

SEM

Expansion factor

Detection rate, %
AA   2.32   6.75 ± 4.59   0.54   2.72   81  
MDS  3.11   8.68 ± 7.6   0.71   3.42   97  
   RA and RARS   3.11   9.54 ± 9.34   1.22   3.46   100  
   RAEB and RAEB-t   3.11   7.78 ± 5.71   0.68   3.09   94  
PNH   3.95   8.45 ± 9.47   1.04   3.26   95  
Hypoplastic BM*  2.62   7.09 ± 5.17   0.49   2.78   84  
Hyperplastic BM
 
3.04
 
9.50 ± 8.79
 
1.03
 
3.54
 
96
 

Diagnosis

No. clones per patient

Average clone, %

SEM

Expansion factor

Detection rate, %
AA   2.32   6.75 ± 4.59   0.54   2.72   81  
MDS  3.11   8.68 ± 7.6   0.71   3.42   97  
   RA and RARS   3.11   9.54 ± 9.34   1.22   3.46   100  
   RAEB and RAEB-t   3.11   7.78 ± 5.71   0.68   3.09   94  
PNH   3.95   8.45 ± 9.47   1.04   3.26   95  
Hypoplastic BM*  2.62   7.09 ± 5.17   0.49   2.78   84  
Hyperplastic BM
 
3.04
 
9.50 ± 8.79
 
1.03
 
3.54
 
96
 

Expansion factor indicates the average fold expansion of VB families above the greater-than-2 SD values derived from healthy controls

SEM indicates standard error of mean; AA, aplastic anemia; MDS, myelodysplastic syndrome; RA, refractory anemia; RARS, refractory anemia with ring sideroblasts; RAEB, refractory anemia with excess of blasts; RAEB-t, RAEB in transformation; PNH, paroxysmal nocturnal hemoglobinuria; and BM, bone marrow

*

Includes AA and MDS

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