Characteristics of the 401 patients included in the study
Characteristic . | CHVP-I arm . | CHOP-ASCT arm . |
|---|---|---|
| No. of patients | 209 | 192 |
| Median age, y | 49 | 49 |
| Male sex, no. (%) | 114 (55) | 107 (56) |
| Performance status, no. (%)* | ||
| 0 | 121 (62) | 114 (63) |
| 1 | 56 (29) | 54 (30) |
| Greater than 1 | 17 (9) | 12 (7) |
| Disease stage, no. (%)* | ||
| II | 16 (8) | 11 (6) |
| III | 26 (13) | 23 (12) |
| IV | 160 (79) | 153 (82) |
| B symptoms, no. (%)* | 58 (30) | 44 (24) |
| Bone marrow involvement, no. (%)* | 143 (73) | 140 (76) |
| Elevated LDH level, no. (%)* | 68 (35) | 64 (34) |
| Elevated β2-microglobulin level, no. (%)* | 85 (46) | 81 (45) |
| Tumor larger than 7 cm, no. (%)* | 135 (67) | 131 (70) |
| FLIPI score, no. (%)* | ||
| Low risk | 63 (32) | 55 (30) |
| Intermediate risk | 67 (34) | 79 (43) |
| High risk | 69 (34) | 51 (27) |
| Histologic findings, no. (%) | ||
| Reviewed | 182 (87) | 173 (91) |
| Follicular | 172 (95) | 167 (96) |
| Grade 1 | 36 (21) | 38 (23) |
| Grade 2 | 116 (68) | 112 (67) |
| Grade 3 | 4 (2) | 3 (2) |
| Unknown | 16 (9) | 14 (8) |
| Other lymphoma subtypes | 10 (5) | 7 (4) |
Characteristic . | CHVP-I arm . | CHOP-ASCT arm . |
|---|---|---|
| No. of patients | 209 | 192 |
| Median age, y | 49 | 49 |
| Male sex, no. (%) | 114 (55) | 107 (56) |
| Performance status, no. (%)* | ||
| 0 | 121 (62) | 114 (63) |
| 1 | 56 (29) | 54 (30) |
| Greater than 1 | 17 (9) | 12 (7) |
| Disease stage, no. (%)* | ||
| II | 16 (8) | 11 (6) |
| III | 26 (13) | 23 (12) |
| IV | 160 (79) | 153 (82) |
| B symptoms, no. (%)* | 58 (30) | 44 (24) |
| Bone marrow involvement, no. (%)* | 143 (73) | 140 (76) |
| Elevated LDH level, no. (%)* | 68 (35) | 64 (34) |
| Elevated β2-microglobulin level, no. (%)* | 85 (46) | 81 (45) |
| Tumor larger than 7 cm, no. (%)* | 135 (67) | 131 (70) |
| FLIPI score, no. (%)* | ||
| Low risk | 63 (32) | 55 (30) |
| Intermediate risk | 67 (34) | 79 (43) |
| High risk | 69 (34) | 51 (27) |
| Histologic findings, no. (%) | ||
| Reviewed | 182 (87) | 173 (91) |
| Follicular | 172 (95) | 167 (96) |
| Grade 1 | 36 (21) | 38 (23) |
| Grade 2 | 116 (68) | 112 (67) |
| Grade 3 | 4 (2) | 3 (2) |
| Unknown | 16 (9) | 14 (8) |
| Other lymphoma subtypes | 10 (5) | 7 (4) |
Data were missing for performance status (27 patients), disease stage (12 patients), B symptoms (25 patients), bone marrow involvement (24 patients), elevated LDH level (19 patients), elevated β2-microglobulin level (36 patients), tumor larger than 7 cm (12 patients), and FLIPI score (17 patients)