Cytokine production and AChE catalytic activity in LPS-injected TgR mice: AThCh hydrolysing activity/min/mg of protein after LPS
. | BM, time after LPS . | . | . | Plasma, time after LPS . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | 0 h . | 24 h . | 72 h . | 0 h . | 24 h . | 72 h . | ||||
| TgR mice | 20 ± 3.0 | 14.2 ± 4.3 | 13.1 ± 1.8 | 87 ± 1.5 | 31.7 ± 12.8 | 7.7 ± 0.4 | ||||
| FVB/N mice | 14 ± 2.7 | 6.3 ± 1.9 | 11.0 ± 0.7 | 15 ± 1.5 | 27.0 ± 13.1 | 9.3 ± 1.0 | ||||
| P | .02 | < .001 | NS | .001 | NS | NS | ||||
. | BM, time after LPS . | . | . | Plasma, time after LPS . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | 0 h . | 24 h . | 72 h . | 0 h . | 24 h . | 72 h . | ||||
| TgR mice | 20 ± 3.0 | 14.2 ± 4.3 | 13.1 ± 1.8 | 87 ± 1.5 | 31.7 ± 12.8 | 7.7 ± 0.4 | ||||
| FVB/N mice | 14 ± 2.7 | 6.3 ± 1.9 | 11.0 ± 0.7 | 15 ± 1.5 | 27.0 ± 13.1 | 9.3 ± 1.0 | ||||
| P | .02 | < .001 | NS | .001 | NS | NS | ||||
AChE catalytic activity assessed by its AThCh hydrolyzing activity/min/mg of protein was measured in plasma and bone marrow cell extracts (BM) of LPS-injected mice (n = 10). Shown are average concentrations ± SD in plasma or BM proteins.
NS indicates not significant.