Table 2.

Nonhematologic toxicities during course 1

Toxicity grade
No. of patients
1
2
3
4
VPA dose, mg/kg      
    20   3   2   1   0   0  
    35   9   1   6   2   0  
    50   10   0   7   2   0  
Phase 2, 50 mg/kg
 		 32
 		 5
 		 16
 		 8
 		 1
 
Toxicity grade
No. of patients
1
2
3
4
VPA dose, mg/kg      
    20   3   2   1   0   0  
    35   9   1   6   2   0  
    50   10   0   7   2   0  
Phase 2, 50 mg/kg
 		 32
 		 5
 		 16
 		 8
 		 1
 
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