Patient characteristics
Characteristic . | All patients . | Untreated patients . |
|---|---|---|
| Median age, y (range) | 60 (5-80) | 71 (62-80) |
| Patients with AML, no. (%) | 48 (89) | 8 (73) |
| Patients with MDS, no. (%) | 6 (11) | 3 (27) |
| Median no. of prior therapies (range) | 2 (0-5) | NA |
| Untreated patients, no. (%) | 11 (20) | NA |
| Patients at first salvage, no. (%) | 15 (28) | NA |
| Patients at second or later salvage, no. (%) | 28 (52) | NA |
| Patients with CR1 at less than 12 mo, no. | 18 | NA |
| At first salvage | 4 | NA |
| At second or later salvage | 14 | NA |
| Patients with CR1 of 12 mo or more, no. | 6 | NA |
| At first salvage | 2 | NA |
| At second or later salvage | 4 | NA |
| Median WBC count, × 109/L (range) | 4.3 (0.6-74.1) | 5.7 (1.4-56.4) |
| Median platelet count, × 109/L (range) | 34 (4-470) | 37 (6-470) |
| Median creatinine level, mM (range) | 79.56 (17.68-167.96) | 97.24 (70.72-159.12) |
| Median total bilirubin level, mM (range) | 8.55 (3.42-32.49) | 10.26 (6.84-30.78) |
| Cytogenetics, no. patients (%) | ||
| Diploid | 24 (44) | 5 (45) |
| Inv(16)/t(8;21) | 2 (4) | 0 (0) |
| +8, -5, -7, other | 28 (52) | 6 (54) |
Characteristic . | All patients . | Untreated patients . |
|---|---|---|
| Median age, y (range) | 60 (5-80) | 71 (62-80) |
| Patients with AML, no. (%) | 48 (89) | 8 (73) |
| Patients with MDS, no. (%) | 6 (11) | 3 (27) |
| Median no. of prior therapies (range) | 2 (0-5) | NA |
| Untreated patients, no. (%) | 11 (20) | NA |
| Patients at first salvage, no. (%) | 15 (28) | NA |
| Patients at second or later salvage, no. (%) | 28 (52) | NA |
| Patients with CR1 at less than 12 mo, no. | 18 | NA |
| At first salvage | 4 | NA |
| At second or later salvage | 14 | NA |
| Patients with CR1 of 12 mo or more, no. | 6 | NA |
| At first salvage | 2 | NA |
| At second or later salvage | 4 | NA |
| Median WBC count, × 109/L (range) | 4.3 (0.6-74.1) | 5.7 (1.4-56.4) |
| Median platelet count, × 109/L (range) | 34 (4-470) | 37 (6-470) |
| Median creatinine level, mM (range) | 79.56 (17.68-167.96) | 97.24 (70.72-159.12) |
| Median total bilirubin level, mM (range) | 8.55 (3.42-32.49) | 10.26 (6.84-30.78) |
| Cytogenetics, no. patients (%) | ||
| Diploid | 24 (44) | 5 (45) |
| Inv(16)/t(8;21) | 2 (4) | 0 (0) |
| +8, -5, -7, other | 28 (52) | 6 (54) |
For all patients, N = 54; for untreated patients, N = 11.
NA indicates not applicable.