Incidence and severity of AOD in the ovarian grafts of NOv-d3tx B6AF1 mice that received 3 × 105 Tregs
. | AOD in ovarian graft . | . | Dacryoadenitis . | . | ||
|---|---|---|---|---|---|---|
| Treg donor . | Incidence, % (n) . | Severity* . | Incidence, % (n) . | Severity* . | ||
| None | 63 (11) | 2.0 ± 0.2 | 72 (11) | 1.5 ± 0.2 | ||
| Female | 8 (12) | 1.5 ± 0 | 0 (12) | – | ||
| Male | 63 (11) | 1.9 ± 0.2 | 0 (11) | – | ||
. | AOD in ovarian graft . | . | Dacryoadenitis . | . | ||
|---|---|---|---|---|---|---|
| Treg donor . | Incidence, % (n) . | Severity* . | Incidence, % (n) . | Severity* . | ||
| None | 63 (11) | 2.0 ± 0.2 | 72 (11) | 1.5 ± 0.2 | ||
| Female | 8 (12) | 1.5 ± 0 | 0 (12) | – | ||
| Male | 63 (11) | 1.9 ± 0.2 | 0 (11) | – | ||
The female recipients were ovariectomized at the day of birth, thymectomized at day 3, received implants of an age-matched syngeneic ovary at week 3, and studied at week 7 to 8. They also received the Tregs at day 5.
Mean ± SD of mice with disease