Cytogenetic analyses of PD839 cells
PD839 cells and clastogen concentration . | Radials, no. (%) . | FA range, % . | Normal range, % . |
|---|---|---|---|
| Fibroblasts | |||
| None | 0 (0) | 0-8 | 0 |
| MMC, 12 ng/mL | 11 (22) | 16-100 | 0 |
| MMC, 20 ng/mL | 25 (50) | 47-67 | 0 |
| DEB, 75 ng/mL | 18 (35) | 20-36 | 0 |
| Lymphocytes | |||
| MMC, 40 ng/mL | 3 (6) | 30-100 | 0-4 |
| DEB, 100 ng/mL | 0 (0) | 0-32 | 0 |
PD839 cells and clastogen concentration . | Radials, no. (%) . | FA range, % . | Normal range, % . |
|---|---|---|---|
| Fibroblasts | |||
| None | 0 (0) | 0-8 | 0 |
| MMC, 12 ng/mL | 11 (22) | 16-100 | 0 |
| MMC, 20 ng/mL | 25 (50) | 47-67 | 0 |
| DEB, 75 ng/mL | 18 (35) | 20-36 | 0 |
| Lymphocytes | |||
| MMC, 40 ng/mL | 3 (6) | 30-100 | 0-4 |
| DEB, 100 ng/mL | 0 (0) | 0-32 | 0 |
MMC/DEB-treated fibroblasts and lymphocytes were scored for formation of chromosomal radials.