Table 5.

Multivariate analysis for survival


Characteristic

Hazard ratio

P
Age   1.03 (1.02-1.03)   <.001  
Performance score 3/4   1.37 (1.08-1.74)   .010  
WBC count   1.003 (1.00-1.004)   .003  
Hgb level   0.92 (0.89-0.96)   .001  
β2-M level   1.04 (1.02-1.06)   .001  
Total bilirubin concentration   1.11 (0.97-1.28)   .13  
Bone marrow blast   0.997 (0.994-1.00)   .034  
LDH level   1.0001 (1.00-1.0004)   <.001  
Cytogenetics   
   Poor vs favorable   4.10 (2.89-5.81)   <.001  
   Others vs favorable   2.38 (1.69-3.34)   <.001  
Treatment in laminar flow room   0.73 (0.63-0.85)   <.001  
M7 AML
 
1.66 (1.09-2.54)
 
.019
 

Characteristic

Hazard ratio

P
Age   1.03 (1.02-1.03)   <.001  
Performance score 3/4   1.37 (1.08-1.74)   .010  
WBC count   1.003 (1.00-1.004)   .003  
Hgb level   0.92 (0.89-0.96)   .001  
β2-M level   1.04 (1.02-1.06)   .001  
Total bilirubin concentration   1.11 (0.97-1.28)   .13  
Bone marrow blast   0.997 (0.994-1.00)   .034  
LDH level   1.0001 (1.00-1.0004)   <.001  
Cytogenetics   
   Poor vs favorable   4.10 (2.89-5.81)   <.001  
   Others vs favorable   2.38 (1.69-3.34)   <.001  
Treatment in laminar flow room   0.73 (0.63-0.85)   <.001  
M7 AML
 
1.66 (1.09-2.54)
 
.019
 

Each characteristic is associated with longer (hazard ratio <1) or shorter (hazard ratio >1) OS time.

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