Diagnostic criteria for XLP
Definitive XLP | Male patients with lymphoma/Hodgkin disease (HD), fatal EBV infection, immunodeficiency, aplastic anemia or lymphohistiocytic disorder who have a mutation in SAP SH2D1A. |
| Probable XLP | Male patients experiencing death, lymphoma/HD, immunodeficiency, aplastic anemia, or lymphohistiocytic disorder following acute EBV infection and maternal cousins, uncles, or nephews with a history of a similar diagnosis following acute EBV infection. |
| Possible XLP | Male patients experiencing death, lymphoma/HD, immunodeficiency, aplastic anemia, or lymphohistiocytic disorder following acute EBV infection; this is sometimes described as sporadic XLP. |
Definitive XLP | Male patients with lymphoma/Hodgkin disease (HD), fatal EBV infection, immunodeficiency, aplastic anemia or lymphohistiocytic disorder who have a mutation in SAP SH2D1A. |
| Probable XLP | Male patients experiencing death, lymphoma/HD, immunodeficiency, aplastic anemia, or lymphohistiocytic disorder following acute EBV infection and maternal cousins, uncles, or nephews with a history of a similar diagnosis following acute EBV infection. |
| Possible XLP | Male patients experiencing death, lymphoma/HD, immunodeficiency, aplastic anemia, or lymphohistiocytic disorder following acute EBV infection; this is sometimes described as sporadic XLP. |