Table 2.

Previously described ISGs confirmed in CD34 and stroma cells by gene-expression microarray





Fold change
GenBank no.
Gene name
Gene symbol
Stroma
CD34
X67325   Interferon alpha–inducible protein 27  IFI27 (IFNa)  59.6   5.0  
U88964   Interferon-stimulated gene, 20 kDa  ISG20  16.1   4.4  
AF026939   Interferon-induced protein with tetratricopeptide repeats 4  IFIT4 (IFNa)  57.1   6.3  
M24594   Interferon-induced protein with tetratricopeptide repeats 1  IFIT1 (IFNb)  17.5   3.7  
U72882   Interferon-induced protein 35  IFI35 (IFNa)  3.1   3.9  
M13755   Interferon alpha–inducible protein (clone IFI-15K)  G1P2 (IFNa,b)  2.2   4.7  
AA203213   Interferon alpha–inducible protein (clone IFI-15K)  G1P2 (IFNa,b)  8.1   6.2  
M14660   Interferon-induced protein with tetratricopeptide repeats 2  IFIT2  78.6   13.1  
L05072   Interferon regulatory factor 1  IRF1  9.4   3.6  
M33882   Myxovirus resistance 1, interferon-inducible protein p78  MX1  43.6   7.1  
M55542   Guanylate binding protein 1, interferon-inducible, 67 kDa  GBP1  12.8   5.9  
J04164   Interferon-induced transmembrane protein 1 (9-27)  IFIM1 (IFNb)  3.5   3.3  
M63838   Interferon gamma–inducible protein 16  IFI16  4.8   2.3  
D28915   Interferon-induced protein 44  IFI44  3.9   3.7  
L78833   Interferon-induced protein 35  IFI35  11.4   3.5  
U34605   Interferon-induced protein with tetratricopeptide repeats 5  IFIT5  3.7   2.2  
J03909   Interferon gamma–inducible protein 30* IFI30  –   2.3  
X57352   Interferon-induced transmembrane protein 3 (1-8U)* IFITM3  –   2.2  
U50648   Protein kinase interferon-inducible double-stranded RNA dependent* PRKR  –   2.2  
J00219   Interferon gamma* IFNG  –   5.4  
U22970   Interferon alpha–inducible protein (clone IFI-6-16)* G1P3 (IFNb)  3.0   –  
M55543
 
Guanylate binding protein 2, interferon-inducible*
 
GBP2
 

 
3.3
 




Fold change
GenBank no.
Gene name
Gene symbol
Stroma
CD34
X67325   Interferon alpha–inducible protein 27  IFI27 (IFNa)  59.6   5.0  
U88964   Interferon-stimulated gene, 20 kDa  ISG20  16.1   4.4  
AF026939   Interferon-induced protein with tetratricopeptide repeats 4  IFIT4 (IFNa)  57.1   6.3  
M24594   Interferon-induced protein with tetratricopeptide repeats 1  IFIT1 (IFNb)  17.5   3.7  
U72882   Interferon-induced protein 35  IFI35 (IFNa)  3.1   3.9  
M13755   Interferon alpha–inducible protein (clone IFI-15K)  G1P2 (IFNa,b)  2.2   4.7  
AA203213   Interferon alpha–inducible protein (clone IFI-15K)  G1P2 (IFNa,b)  8.1   6.2  
M14660   Interferon-induced protein with tetratricopeptide repeats 2  IFIT2  78.6   13.1  
L05072   Interferon regulatory factor 1  IRF1  9.4   3.6  
M33882   Myxovirus resistance 1, interferon-inducible protein p78  MX1  43.6   7.1  
M55542   Guanylate binding protein 1, interferon-inducible, 67 kDa  GBP1  12.8   5.9  
J04164   Interferon-induced transmembrane protein 1 (9-27)  IFIM1 (IFNb)  3.5   3.3  
M63838   Interferon gamma–inducible protein 16  IFI16  4.8   2.3  
D28915   Interferon-induced protein 44  IFI44  3.9   3.7  
L78833   Interferon-induced protein 35  IFI35  11.4   3.5  
U34605   Interferon-induced protein with tetratricopeptide repeats 5  IFIT5  3.7   2.2  
J03909   Interferon gamma–inducible protein 30* IFI30  –   2.3  
X57352   Interferon-induced transmembrane protein 3 (1-8U)* IFITM3  –   2.2  
U50648   Protein kinase interferon-inducible double-stranded RNA dependent* PRKR  –   2.2  
J00219   Interferon gamma* IFNG  –   5.4  
U22970   Interferon alpha–inducible protein (clone IFI-6-16)* G1P3 (IFNb)  3.0   –  
M55543
 
Guanylate binding protein 2, interferon-inducible*
 
GBP2
 

 
3.3
 

– indicates that the gene altered the expression level less than 2-fold, or that there was no change.

*

Altered gene expression detected in only one cell type

or Create an Account

Close Modal
Close Modal