Overview of BCL6, PAX5, RhoH/TTF, and MYC mutations in PCFCL
. | Survival . | . | . | Mutation, position* . | . | . | . | . | . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | . | BCL6 . | . | PAX5 . | . | RhoH/TTF . | . | MYC . | . | ||||||||
| Case . | Status . | Time, mo . | AID . | No. . | Mutations . | No. . | Mutations . | No. . | Mutations . | No. . | Mutations . | ||||||||
| 1 | D0 | 28 | ND | 1 | g.751C>A | 0 | NA | 0 | NA | 1 | g.2480G>T | ||||||||
| 2 | A0 | 78 | ND | 1 | g.842T>C | 3 | g.739C>T, g.846C>T, g.848C>T | 3 | g.744C>G, g.816G>A, g.901T>C | 0 | NA | ||||||||
| 3 | A0 | 264 | Occasional | 0 | NA | 2 | g.1082C>T, g.1187C>T | 0 | NA | 0 | NA | ||||||||
| 4 | A+ | 86 | Negative | 0 | NA | 1 | g.714_715insT | 0 | NA | 0 | NA | ||||||||
| 5 | A0 | 35 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 6 | A0 | 30 | ND | 1 | g.683-695del | 1 | g.839-855del | 0 | NA | 1 | g.2739G>T | ||||||||
| 7 | A0 | 28 | Negative | 1 | g.713G>A | 0 | NA | 2 | g.469A>G, g.609G>A | 1 | g.2710C>T | ||||||||
| 8 | A0 | 23 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 9 | A0 | 42 | ND | 1 | g.798G>A | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 10 | A0 | 74 | ND | 2 | g.766C>A, g.809G>A | 7 | g.893C>T, g.1046C>T, g.1206G>A, g.1223G>A, g.1338C>G, g.1357C>G, g.1435G>C | 0 | NA | 1 | g.2541C>A | ||||||||
| 11 | A0 | 63 | Occasional | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 12 | A0 | 57 | Negative | 0 | NA | 0 | NA | 0 | NA | 1 | g.2466A>G | ||||||||
| 13 | A0 | 62 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 14 | A0 | 69 | ND | 1 | g.759G>A | 0 | NA | 0 | NA | 1 | g.2366C>T | ||||||||
| 15 | D0 | 70 | Negative | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 16 | A0 | 52 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 17 | A0 | 40 | Negative | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 18 | D+ | 130 | Negative | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 19 | A0 | 113 | ND | 0 | NA | 0 | NA | 0 | NA | 1 | g.2616C>G | ||||||||
. | Survival . | . | . | Mutation, position* . | . | . | . | . | . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | . | BCL6 . | . | PAX5 . | . | RhoH/TTF . | . | MYC . | . | ||||||||
| Case . | Status . | Time, mo . | AID . | No. . | Mutations . | No. . | Mutations . | No. . | Mutations . | No. . | Mutations . | ||||||||
| 1 | D0 | 28 | ND | 1 | g.751C>A | 0 | NA | 0 | NA | 1 | g.2480G>T | ||||||||
| 2 | A0 | 78 | ND | 1 | g.842T>C | 3 | g.739C>T, g.846C>T, g.848C>T | 3 | g.744C>G, g.816G>A, g.901T>C | 0 | NA | ||||||||
| 3 | A0 | 264 | Occasional | 0 | NA | 2 | g.1082C>T, g.1187C>T | 0 | NA | 0 | NA | ||||||||
| 4 | A+ | 86 | Negative | 0 | NA | 1 | g.714_715insT | 0 | NA | 0 | NA | ||||||||
| 5 | A0 | 35 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 6 | A0 | 30 | ND | 1 | g.683-695del | 1 | g.839-855del | 0 | NA | 1 | g.2739G>T | ||||||||
| 7 | A0 | 28 | Negative | 1 | g.713G>A | 0 | NA | 2 | g.469A>G, g.609G>A | 1 | g.2710C>T | ||||||||
| 8 | A0 | 23 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 9 | A0 | 42 | ND | 1 | g.798G>A | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 10 | A0 | 74 | ND | 2 | g.766C>A, g.809G>A | 7 | g.893C>T, g.1046C>T, g.1206G>A, g.1223G>A, g.1338C>G, g.1357C>G, g.1435G>C | 0 | NA | 1 | g.2541C>A | ||||||||
| 11 | A0 | 63 | Occasional | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 12 | A0 | 57 | Negative | 0 | NA | 0 | NA | 0 | NA | 1 | g.2466A>G | ||||||||
| 13 | A0 | 62 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 14 | A0 | 69 | ND | 1 | g.759G>A | 0 | NA | 0 | NA | 1 | g.2366C>T | ||||||||
| 15 | D0 | 70 | Negative | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 16 | A0 | 52 | ND | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 17 | A0 | 40 | Negative | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 18 | D+ | 130 | Negative | 0 | NA | 0 | NA | 0 | NA | 0 | NA | ||||||||
| 19 | A0 | 113 | ND | 0 | NA | 0 | NA | 0 | NA | 1 | g.2616C>G | ||||||||
A0 indicates alive without disease; A+, alive with disease; D0, death unrelated to lymphoma; D+, death related to lymphoma; negative, no tumor cells stained; occasional, less than 10% of tumor cells stained; NA, not applicable; and ND, not determined.