Comparison of results in cobalamin-deficient patients with and without neurologic abnormalities
| . | With neurologic abnormalities, n = 11 . | Without neurologic abnormalities, n = 11 . |
|---|---|---|
| Total homocysteine level, μM | 97.6 ± 60.8 (104.3) | 98.5 ± 50.2 (88.9) |
| S-adenosylmethionine level, nM | 117.2 ± 24.7* (126.5) | 78.6 ± 26.6* (80.5) |
| Methionine level, μM | 20.7 ± 10.4 (18.3) | 23.9 ± 9.8 (20.4) |
| Cysteine level, μM | 462 ± 90† (449) | 325 ± 73†(297) |
| Cysteinylglycine level, μM | 85.0 ± 24.5‡(88.0) | 54.7 ± 13.0‡ (52.5) |
| Glutathione level, μM | 2.3 ± 1.4 (1.9) | 1.9 ± 1.2 (2.0) |
| Cobalamin level, pM | 32 ± 29 (31) | 35 ± 39 (37) |
| Folate level, nM | 27.9 ± 12.52-153 (29.0) | 15.4 ± 7.52-153 (17.9) |
| Hemoglobin level, g/L | 108 ± 452-153(118) | 63 ± 312-153 (52) |
| MCV, fL | 109 ± 19 (111) | 110 ± 14 (115) |
| . | With neurologic abnormalities, n = 11 . | Without neurologic abnormalities, n = 11 . |
|---|---|---|
| Total homocysteine level, μM | 97.6 ± 60.8 (104.3) | 98.5 ± 50.2 (88.9) |
| S-adenosylmethionine level, nM | 117.2 ± 24.7* (126.5) | 78.6 ± 26.6* (80.5) |
| Methionine level, μM | 20.7 ± 10.4 (18.3) | 23.9 ± 9.8 (20.4) |
| Cysteine level, μM | 462 ± 90† (449) | 325 ± 73†(297) |
| Cysteinylglycine level, μM | 85.0 ± 24.5‡(88.0) | 54.7 ± 13.0‡ (52.5) |
| Glutathione level, μM | 2.3 ± 1.4 (1.9) | 1.9 ± 1.2 (2.0) |
| Cobalamin level, pM | 32 ± 29 (31) | 35 ± 39 (37) |
| Folate level, nM | 27.9 ± 12.52-153 (29.0) | 15.4 ± 7.52-153 (17.9) |
| Hemoglobin level, g/L | 108 ± 452-153(118) | 63 ± 312-153 (52) |
| MCV, fL | 109 ± 19 (111) | 110 ± 14 (115) |
Values are shown as mean ± SD and, in parentheses, median. Significant differences are highlighted in boldface type.
Significant difference between the 2 groups' values,P = .002.
Significant difference between the 2 groups' values,P = .001.
Significant difference between the 2 groups' values,P = .004.
Significant difference between the 2 groups' values,P = .02.