Cycling status of NOD/SL-ICs as determined by3H-Tdr suicide assay
| Patient . | % CD45+ cells in mouse BM (mean ± SD) . | % kill by 3H-Tdr . | |
|---|---|---|---|
| Control3-150 (no. of mice tested) . | With 3H-Tdr3-150 (no. of mice tested) . | ||
| 1 | 1.2 ± 1.4 (6) | 0.69 ± 0.60 (6) | 38 |
| 2 | 93.0 ± 8.7 (5) | 97.1 ± 2.8 (4) | 0 |
| 3 | 3.9 ± 7.8 (6) | 2.2 ± 2.6 (6) | 43 |
| 4 | 9.5 ± 10.4 (5) | 7.1 ± 4.3 (5) | 26 |
| 5 | 81.0 ± 12.8 (6) | 64.4 ± 22.1 (6) | 20 |
| 6 | 7.9 ± 8.1 (4) | 6.6 ± 8.4 (3) | 16 |
| 7 | 18.7 ± 12.6 (4) | 3.6 ± 1.5 (4) | 82 |
| Patient . | % CD45+ cells in mouse BM (mean ± SD) . | % kill by 3H-Tdr . | |
|---|---|---|---|
| Control3-150 (no. of mice tested) . | With 3H-Tdr3-150 (no. of mice tested) . | ||
| 1 | 1.2 ± 1.4 (6) | 0.69 ± 0.60 (6) | 38 |
| 2 | 93.0 ± 8.7 (5) | 97.1 ± 2.8 (4) | 0 |
| 3 | 3.9 ± 7.8 (6) | 2.2 ± 2.6 (6) | 43 |
| 4 | 9.5 ± 10.4 (5) | 7.1 ± 4.3 (5) | 26 |
| 5 | 81.0 ± 12.8 (6) | 64.4 ± 22.1 (6) | 20 |
| 6 | 7.9 ± 8.1 (4) | 6.6 ± 8.4 (3) | 16 |
| 7 | 18.7 ± 12.6 (4) | 3.6 ± 1.5 (4) | 82 |
Percent CD45+ cells in BM of mice injected 8 weeks previously with 107 AML cells cultured overnight with or without the addition of 3H-Tdr.