Comparison of clinical and laboratory data between the two major patient subgroups defined by hierarchical cluster analysis
| Variable . | Ribosomal cluster . | Other patients . | P . |
|---|---|---|---|
| No. patients (%) | 20 (26.3) | 56 (73.7) | — |
| Median age, y | 64.5 | 69.5 | .133* |
| Disease stage | |||
| Binet A (%) | 9 of 20 (45.0) | 22 of 55 (40.0) | .315† |
| Binet B (%) | 8 of 20 (40.0) | 13 of 55 (24.0) | — |
| Binet C (%) | 3 of 20 (15.0) | 20 of 55 (36.0) | — |
| White blood cell count, × 10−3/μL | 61.4 ± 49.9 | 41.7 ± 85.9 | .854* |
| Hemoglobin level, g/dL | 14.6 ± 2.0 | 12.0 ± 2.2 | .0005* |
| Platelet count, ×10−3/μL | 171.0 ± 40.6 | 131.0 ± 83.2 | .158* |
| Bone marrow histology, % infiltration | 45.0 ± 24.5 | 60.0 ± 31.8 | .473* |
| CD38+ patients (%) | 5 of 20 (25.0) | 20 of 50 (40.0) | .280† |
| Thymidine kinase level, IU/L | 7.7 ± 10.1 | 13.9 ± 30.6 | .373* |
| β2-microglobulin, mg/L | 1.84 ± 1.86 | 2.76 ± 2.0 | .09* |
| Lactate dehydrogenase level, IU/L | 205.0 ± 65.9 | 231.5 ± 68.4 | .233* |
| Variable . | Ribosomal cluster . | Other patients . | P . |
|---|---|---|---|
| No. patients (%) | 20 (26.3) | 56 (73.7) | — |
| Median age, y | 64.5 | 69.5 | .133* |
| Disease stage | |||
| Binet A (%) | 9 of 20 (45.0) | 22 of 55 (40.0) | .315† |
| Binet B (%) | 8 of 20 (40.0) | 13 of 55 (24.0) | — |
| Binet C (%) | 3 of 20 (15.0) | 20 of 55 (36.0) | — |
| White blood cell count, × 10−3/μL | 61.4 ± 49.9 | 41.7 ± 85.9 | .854* |
| Hemoglobin level, g/dL | 14.6 ± 2.0 | 12.0 ± 2.2 | .0005* |
| Platelet count, ×10−3/μL | 171.0 ± 40.6 | 131.0 ± 83.2 | .158* |
| Bone marrow histology, % infiltration | 45.0 ± 24.5 | 60.0 ± 31.8 | .473* |
| CD38+ patients (%) | 5 of 20 (25.0) | 20 of 50 (40.0) | .280† |
| Thymidine kinase level, IU/L | 7.7 ± 10.1 | 13.9 ± 30.6 | .373* |
| β2-microglobulin, mg/L | 1.84 ± 1.86 | 2.76 ± 2.0 | .09* |
| Lactate dehydrogenase level, IU/L | 205.0 ± 65.9 | 231.5 ± 68.4 | .233* |