Genotype distributions and carrier and allele frequencies of FII 20210A, FVL, and FXIII-A Val34Leu in MI patient and healthy control populations
. | Genotype . | MI, n = 500 (%) . | HC, n = 500 (%) . | OR . | P . |
---|---|---|---|---|---|
G/G | 484 (96.8) | 495 (99.0) | — | — | |
FII 20210A | G/A | 16 (3.2) | 5 (1.0) | — | — |
A/A | 0 (0) | 0 (0) | — | — | |
Carrier F | — | 3.2% | 1.0% | 3.3 | .015 |
Allele F | — | 1.6% | 0.5% | — | — |
R/R | 477 (95.4) | 477 (95.4) | — | — | |
FVL Arg506Gln | R/Q | 23 (4.6) | 23 (4.6) | — | — |
Q/Q | 0 (0) | 0 (0) | — | — | |
Carrier F | — | 4.6% | 4.6% | 1.00 | NS |
Allele F | — | 2.3% | 2.3% | — | — |
V/V | 265 (53.0) | 261 (52.2) | — | — | |
FXIII-A Val34Leu | V/L | 193 (38.6) | 207 (41.4) | — | — |
L/L | 42 (8.4) | 32 (6.4) | — | — | |
Carrier F | — | 47.0% | 47.8% | 0.97 | NS |
Allele F | — | 27.7% | 27.1% | — | — |
. | Genotype . | MI, n = 500 (%) . | HC, n = 500 (%) . | OR . | P . |
---|---|---|---|---|---|
G/G | 484 (96.8) | 495 (99.0) | — | — | |
FII 20210A | G/A | 16 (3.2) | 5 (1.0) | — | — |
A/A | 0 (0) | 0 (0) | — | — | |
Carrier F | — | 3.2% | 1.0% | 3.3 | .015 |
Allele F | — | 1.6% | 0.5% | — | — |
R/R | 477 (95.4) | 477 (95.4) | — | — | |
FVL Arg506Gln | R/Q | 23 (4.6) | 23 (4.6) | — | — |
Q/Q | 0 (0) | 0 (0) | — | — | |
Carrier F | — | 4.6% | 4.6% | 1.00 | NS |
Allele F | — | 2.3% | 2.3% | — | — |
V/V | 265 (53.0) | 261 (52.2) | — | — | |
FXIII-A Val34Leu | V/L | 193 (38.6) | 207 (41.4) | — | — |
L/L | 42 (8.4) | 32 (6.4) | — | — | |
Carrier F | — | 47.0% | 47.8% | 0.97 | NS |
Allele F | — | 27.7% | 27.1% | — | — |
HC indicates healthy control; NS, not significant; and —, not applicable.