Table 6. Response to therapy in patients... | American Society of Hematology

Table 6.

Response to therapy in patients with POEMS syndrome

Treatment	No. of patients	Response to treatment, %
Treatment	No. of patients	Improved	Stable	Progression	Unknown
Radiation	70^6-151	54	4	16	26
Melphalan and prednisone	48	44	12	12	31
Combination chemotherapy^6-150	15	27	7	33	33
Cyclosporine or azathioprine	4	0	0	100	0
Cyclosporine or azathioprine, plus prednisone	6	50	0	17	33
Prednisone or dexamethasone	41	15	7	20	59
Plasmapheresis	16	0	12	87	0
Plasmapheresis plus prednisone	14	21	0	14	64
Intravenous immunoglobulin	9	0	0	89	11

Treatment	No. of patients	Response to treatment, %
Treatment	No. of patients	Improved	Stable	Progression	Unknown
Radiation	70^6-151	54	4	16	26
Melphalan and prednisone	48	44	12	12	31
Combination chemotherapy^6-150	15	27	7	33	33
Cyclosporine or azathioprine	4	0	0	100	0
Cyclosporine or azathioprine, plus prednisone	6	50	0	17	33
Prednisone or dexamethasone	41	15	7	20	59
Plasmapheresis	16	0	12	87	0
Plasmapheresis plus prednisone	14	21	0	14	64
Intravenous immunoglobulin	9	0	0	89	11

F6-150

Includes vincristine, carmustine, melphalan, cyclophosphamide, and prednisone; vincristine, doxorubicin, and dexamethasone; cyclophosphamide, doxorubicin, vincristine, and prednisone; and cyclophospharnide-based chemotherapy.

F6-151

Sixty-four patients were treated with 70 courses of radiation.

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