Engraftment, transduction, and clonality of SF1m-transduced PBPCs in NOD/SCID mice
Donor no. . | Chimeric mouse no. . | Human CD45+ cells in BM, % . | MDR1 provirus–marked human cells in BM, % . | Rh123dull cells, % . | Sequenced clones . | Mapped clones . |
---|---|---|---|---|---|---|
1 | E3 M7 | 36.1 | 9.4 | 4.7 | 32 | 30 |
E3 M10 | 43.0 | 9.0 | 5.5 | 14 | 12 | |
E3 M11 | 30.1 | 10.3 | 7.2 | 17 | 16 | |
E3 M12 | 38.0 | 7.4 | 6.6 | 9 | 8 | |
E3 M14 | 31.6 | 10.6 | 6.6 | 25 | 22 | |
2 | S29 M3 | 29.1 | 35.0 | 14.6 | 7 | 7 |
S29 M5 | 20.6 | 21.0 | 11.9 | 4 | 4 | |
S29 M6 | 32.1 | 11.9 | 13.1 | 3 | 3 | |
3 | E15 M1 | 34.8 | 21.7 | 9.5 | 13 | 12 |
E15 M5 | 13.25 | 30.5 | 9.9 | 8 | 5 | |
E15 M6 | 8.9 | 23.3 | 8.5 | 6 | 4 | |
E15 M15 | 8.6 | 17.6 | 5.5 | 7 | 7 | |
E15 M18 | 12.1 | 21.1 | 6.9 | 11 | 11 |
Donor no. . | Chimeric mouse no. . | Human CD45+ cells in BM, % . | MDR1 provirus–marked human cells in BM, % . | Rh123dull cells, % . | Sequenced clones . | Mapped clones . |
---|---|---|---|---|---|---|
1 | E3 M7 | 36.1 | 9.4 | 4.7 | 32 | 30 |
E3 M10 | 43.0 | 9.0 | 5.5 | 14 | 12 | |
E3 M11 | 30.1 | 10.3 | 7.2 | 17 | 16 | |
E3 M12 | 38.0 | 7.4 | 6.6 | 9 | 8 | |
E3 M14 | 31.6 | 10.6 | 6.6 | 25 | 22 | |
2 | S29 M3 | 29.1 | 35.0 | 14.6 | 7 | 7 |
S29 M5 | 20.6 | 21.0 | 11.9 | 4 | 4 | |
S29 M6 | 32.1 | 11.9 | 13.1 | 3 | 3 | |
3 | E15 M1 | 34.8 | 21.7 | 9.5 | 13 | 12 |
E15 M5 | 13.25 | 30.5 | 9.9 | 8 | 5 | |
E15 M6 | 8.9 | 23.3 | 8.5 | 6 | 4 | |
E15 M15 | 8.6 | 17.6 | 5.5 | 7 | 7 | |
E15 M18 | 12.1 | 21.1 | 6.9 | 11 | 11 |