Ratios comparing A phagocytophila DNA in ticks and skin (suture site, tick site) to A phagocytophila DNA in blood
| Mouse strain ID . | Hours after infestation . | Suture . | Tick skin . | Ticks . | |||
|---|---|---|---|---|---|---|---|
| Ave ± SE* . | P† . | Ave ± SE . | P . | Ave ± SE . | P . | ||
| B6 | 24 | 37.1 ± 13.1 | — | 0.11 ± 0.028 | — | 0.007 ± 0.004 | — |
| CD11b−/− | 24 | 5.5 ± 2.4 | .007 | 0.07 ± 0.002 | .28 | 0.002 ± 0.001 | .10 |
| CD11a−/− | 24 | 7.7 ± 1.8 | .011 | 0.03 ± 0.007 | .16 | 0.001 ± 0.001 | .07 |
| B6 | 48 | 1.5 ± 0.7 | — | 0.07 ± 0.016 | — | 0.003 ± 0.002 | — |
| CD11b−/− | 48 | 4.8 ± 2.2 | .08 | 0.11 ± 0.042 | .52 | 0.008 ± 0.007 | .38 |
| CD11a−/− | 48 | 1.2 ± 0.6 | .63 | 0.07 ± 0.012 | .95 | 0.0001 ± 0.0001 | .11 |
| B6 | 72 | 0.7 ± 0.2 | — | 0.16 ± 0.039 | — | 0.052 ± 0.018 | — |
| CD11b−/− | 72 | 5.2 ± 1.3 | .10 | 0.07 ± 0.035 | .12 | 0.030 ± 0.017 | .53 |
| CD11a−/− | 72 | 5.1 ± 1.8 | .17 | 0.11‡ | n/a | 0.001 ± 0.0002 | .02 |
| Mouse strain ID . | Hours after infestation . | Suture . | Tick skin . | Ticks . | |||
|---|---|---|---|---|---|---|---|
| Ave ± SE* . | P† . | Ave ± SE . | P . | Ave ± SE . | P . | ||
| B6 | 24 | 37.1 ± 13.1 | — | 0.11 ± 0.028 | — | 0.007 ± 0.004 | — |
| CD11b−/− | 24 | 5.5 ± 2.4 | .007 | 0.07 ± 0.002 | .28 | 0.002 ± 0.001 | .10 |
| CD11a−/− | 24 | 7.7 ± 1.8 | .011 | 0.03 ± 0.007 | .16 | 0.001 ± 0.001 | .07 |
| B6 | 48 | 1.5 ± 0.7 | — | 0.07 ± 0.016 | — | 0.003 ± 0.002 | — |
| CD11b−/− | 48 | 4.8 ± 2.2 | .08 | 0.11 ± 0.042 | .52 | 0.008 ± 0.007 | .38 |
| CD11a−/− | 48 | 1.2 ± 0.6 | .63 | 0.07 ± 0.012 | .95 | 0.0001 ± 0.0001 | .11 |
| B6 | 72 | 0.7 ± 0.2 | — | 0.16 ± 0.039 | — | 0.052 ± 0.018 | — |
| CD11b−/− | 72 | 5.2 ± 1.3 | .10 | 0.07 ± 0.035 | .12 | 0.030 ± 0.017 | .53 |
| CD11a−/− | 72 | 5.1 ± 1.8 | .17 | 0.11‡ | n/a | 0.001 ± 0.0002 | .02 |
Ave indicates average; —, not applicable; and n/a, not available.
Ratio calculated as (p44 DNA per milligram of skin at suture site [or per milligram of tick skin or per tick])/(p44 DNA per milliliter of blood × 100)
P compares CD11b−/− and CD11a−/− mice with B6 wild-type controls.
n = 1; other ticks attached exclusively to head sites at this time point; therefore, they were not included in analysis.