Patient, donor, and transplant characteristics
Median age, y (range) | 5 (1-20) |
Median weight, kg (range) | 18 (9-45) |
Sex, male/female | 19/25 |
Thalassemia/SCD | 33/11 |
Pesaro class at time of CBT (only for patients with thalassemia) | |
Class 1 | 20 (61%) |
Class 2 | 13 (39%) |
CMV serology | |
Negative | 18 (41%) |
Positive | 26 (59%) |
ABO compatibility | |
Matched | 27 (61%) |
Mismatched | 17 (39%) |
Median number of nucleated cells collected, 107/kg of recipient (range) | 5.1 (1.2-13) |
Median number of nucleated cells infused, 107/kg of recipient (range) | 4.0 (1.2-10) |
Conditioning | |
SCD | |
BU/CY | 10 |
(associated to ATG/ALG) | 8 |
BU/FLU/TT | 1 |
Thalassemia | |
BU/CY | 16 |
(associated to ATG/ALG) | 10 |
BU/CY/TT | 9 |
BU/CY/FLU | 1 |
BU/FLU/TT | 7 |
GVHD prophylaxis | |
CsA | 30 |
CsA + steroids | 2 |
CsA + MTX | 10 |
Tacrolimus + MTX | 1 |
MMF + MTX | 1 |
Median age, y (range) | 5 (1-20) |
Median weight, kg (range) | 18 (9-45) |
Sex, male/female | 19/25 |
Thalassemia/SCD | 33/11 |
Pesaro class at time of CBT (only for patients with thalassemia) | |
Class 1 | 20 (61%) |
Class 2 | 13 (39%) |
CMV serology | |
Negative | 18 (41%) |
Positive | 26 (59%) |
ABO compatibility | |
Matched | 27 (61%) |
Mismatched | 17 (39%) |
Median number of nucleated cells collected, 107/kg of recipient (range) | 5.1 (1.2-13) |
Median number of nucleated cells infused, 107/kg of recipient (range) | 4.0 (1.2-10) |
Conditioning | |
SCD | |
BU/CY | 10 |
(associated to ATG/ALG) | 8 |
BU/FLU/TT | 1 |
Thalassemia | |
BU/CY | 16 |
(associated to ATG/ALG) | 10 |
BU/CY/TT | 9 |
BU/CY/FLU | 1 |
BU/FLU/TT | 7 |
GVHD prophylaxis | |
CsA | 30 |
CsA + steroids | 2 |
CsA + MTX | 10 |
Tacrolimus + MTX | 1 |
MMF + MTX | 1 |
MMF indicates mycophenolate mofetil.