Table 1.

Patient, donor, and transplant characteristics

Median age, y (range) 5 (1-20)  
Median weight, kg (range) 18 (9-45)  
Sex, male/female 19/25 
Thalassemia/SCD 33/11  
Pesaro class at time of CBT (only for patients with thalassemia)  
 Class 1 20 (61%) 
 Class 2 13 (39%)  
CMV serology  
 Negative 18 (41%)  
 Positive 26 (59%) 
ABO compatibility  
 Matched 27 (61%) 
 Mismatched 17 (39%)  
Median number of nucleated cells collected, 107/kg of recipient
(range) 
5.1 (1.2-13)  
Median number of nucleated cells infused, 107/kg of recipient
(range) 
4.0 (1.2-10) 
Conditioning  
 SCD  
  BU/CY 10 
   (associated to ATG/ALG)  8  
  BU/FLU/TT  1 
 Thalassemia  
  BU/CY 16  
   (associated to ATG/ALG) 10  
  BU/CY/TT  9  
  BU/CY/FLU  1 
  BU/FLU/TT  7  
 GVHD prophylaxis  
  CsA 30 
  CsA + steroids  2  
  CsA + MTX 10 
  Tacrolimus + MTX  1  
  MMF + MTX  1 
Median age, y (range) 5 (1-20)  
Median weight, kg (range) 18 (9-45)  
Sex, male/female 19/25 
Thalassemia/SCD 33/11  
Pesaro class at time of CBT (only for patients with thalassemia)  
 Class 1 20 (61%) 
 Class 2 13 (39%)  
CMV serology  
 Negative 18 (41%)  
 Positive 26 (59%) 
ABO compatibility  
 Matched 27 (61%) 
 Mismatched 17 (39%)  
Median number of nucleated cells collected, 107/kg of recipient
(range) 
5.1 (1.2-13)  
Median number of nucleated cells infused, 107/kg of recipient
(range) 
4.0 (1.2-10) 
Conditioning  
 SCD  
  BU/CY 10 
   (associated to ATG/ALG)  8  
  BU/FLU/TT  1 
 Thalassemia  
  BU/CY 16  
   (associated to ATG/ALG) 10  
  BU/CY/TT  9  
  BU/CY/FLU  1 
  BU/FLU/TT  7  
 GVHD prophylaxis  
  CsA 30 
  CsA + steroids  2  
  CsA + MTX 10 
  Tacrolimus + MTX  1  
  MMF + MTX  1 

MMF indicates mycophenolate mofetil.

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