v2LDGs: LDGs showing similar expression patterns in bone marrow PC and subsets of MM
| Accession no. . | Symbol . | Function . | Quantitative gene expression . | |
|---|---|---|---|---|
| BPCs . | MM . | |||
| U61145 | EZH2 | Transcription; SET domain | − | −/+ |
| HT4000 | SYK | Signaling; lymphocyte kinase | − | −/++ |
| X89986 | BIK | Signaling; apoptosis inducer | − | −/++++ |
| D85181 | SC5DL | Metabolism; sterol-C5-desaturase | + | −/+ |
| M98045 | FPGS | Metabolism; folylpolyglutamate synthase | + | −/++ |
| L41559 | PCBD | Transcription; enhances TCF1 activity | + | −/++ |
| L25876 | CDKN2 | Cell cycle; CDK inhibitor; phosphatase | + | +/++ |
| U76638 | BRAD1 | Transcription; BRCA1 heterodimer | + | +/++ |
| L05072 | IRF1 | Transcription; IRF family | + | +/++ |
| D87440 | KIAA0252a | Unknown | + | +/++ |
| U02680 | PTK9 | Tyrosine kinase | + | +/++ |
| U28042 | DDX10 | Oncogene; ATP-dependent RNA helicase | + | +/++ |
| L20320 | CDK7 | Cell cycle; kinase | + | +/++ |
| X56494 | PKM2 | Metabolism; pyruvate kinase | + | +/++++ |
| M12959 | TCRA | Signaling; T-cell receptor | ++ | −/++ |
| HT3981 | INSL3 | Signaling; insulinlike peptide; IGF family | ++ | −/++ |
| U21931 | FBP1 | Metabolism; fructose bisphophatase | ++ | −/++++ |
| Z48054 | PXR1 | Metabolism; peroxisome biogenesis | ++ | +/++ |
| D84145 | WS-3a | Dynatin 6 | ++ | +/++ |
| D14661 | KIAA0105a | Transcription; WT1-associating protein | ++ | +/++ |
| X77548 | NCOA4 | Transcription; nuclear receptor coactivator | ++ | +/++ |
| M90696 | CTSS | Cysteine protease | ++ | +/++ |
| D11086 | IL2RG | Cytokine receptor | ++ | +/++ |
| U70426 | RGS16 | Signaling; GTPase activating protein | ++ | +/+++ |
| X14850 | H2AX | Histone; required for antibody maturation | ++ | +/+++ |
| M29927 | OAT | Metabolism; ornithine aminotransferase | ++ | +/+++ |
| S74017 | NFE2L2 | Transcription | ++ | +/+++ |
| HT4604 | GYG | Metabolism; glycogen biogenesis | ++ | +/+++ |
| M55531 | SLC2A5 | Metabolism; fructose transporter | ++ | +/++++ |
| M60750 | H2BFL | Histone; nucleosome | ++ | +/++++ |
| L19437 | TALDO1 | Metabolism; transaldolase | ++ | ++/+++ |
| M10901 | NR3C1 | Transcription; glucocorticoid receptor | ++ | ++/+++ |
| L41887 | SFRS7 | mRNA splicing factor | ++ | ++/+++ |
| M34423 | GLB1 | Metabolism; galactosidase | ++ | ++/++++ |
| X15414 | AKR1B1 | Metabolism; aldose reductase | +++ | +/++++ |
| J04456 | LGALS1 | Signaling; inhibits CD45 phosphatase | +++ | +/++++ |
| X92493 | PIP5K1B | Signaling; kinase | +++ | +/++++ |
| U51478 | ATP1B3 | Na+, K+transporter | +++ | ++/++++ |
| X91257 | SARS | Seryl-tRNA synthetase | +++ | ++/++++ |
| D30655 | EIF4A2 | Translation initiation | +++ | ++/++++ |
| D31887 | KIAA0062a | Unknown | +++ | ++/++++ |
| X04106 | CAPN4 | Cysteine protease; calcium dependent | +++ | ++/++++ |
| D87442 | NCSTNa | Nicastrin | +++ | ++/++++ |
| L76191 | IRAK1 | Signaling; cytokine receptor kinase | +++ | +++/++++ |
| HT1428 | HBB | Hemoglobin | ++++ | −/++++ |
| U44975 | COPEB | Oncogene; transcription factor | ++++ | −/++++ |
| X55733 | EIF4B | Translation initiation | ++++ | +/++++ |
| L09604 | PLP2 | Signaling; colonic epithelium differentiation | ++++ | +/++++ |
| HT1614 | PPP1CA | Signaling; phosphatase | ++++ | +++/++++ |
| L26247 | SUI1a | Translation initiation; probable | ++++ | +++/++++ |
| Accession no. . | Symbol . | Function . | Quantitative gene expression . | |
|---|---|---|---|---|
| BPCs . | MM . | |||
| U61145 | EZH2 | Transcription; SET domain | − | −/+ |
| HT4000 | SYK | Signaling; lymphocyte kinase | − | −/++ |
| X89986 | BIK | Signaling; apoptosis inducer | − | −/++++ |
| D85181 | SC5DL | Metabolism; sterol-C5-desaturase | + | −/+ |
| M98045 | FPGS | Metabolism; folylpolyglutamate synthase | + | −/++ |
| L41559 | PCBD | Transcription; enhances TCF1 activity | + | −/++ |
| L25876 | CDKN2 | Cell cycle; CDK inhibitor; phosphatase | + | +/++ |
| U76638 | BRAD1 | Transcription; BRCA1 heterodimer | + | +/++ |
| L05072 | IRF1 | Transcription; IRF family | + | +/++ |
| D87440 | KIAA0252a | Unknown | + | +/++ |
| U02680 | PTK9 | Tyrosine kinase | + | +/++ |
| U28042 | DDX10 | Oncogene; ATP-dependent RNA helicase | + | +/++ |
| L20320 | CDK7 | Cell cycle; kinase | + | +/++ |
| X56494 | PKM2 | Metabolism; pyruvate kinase | + | +/++++ |
| M12959 | TCRA | Signaling; T-cell receptor | ++ | −/++ |
| HT3981 | INSL3 | Signaling; insulinlike peptide; IGF family | ++ | −/++ |
| U21931 | FBP1 | Metabolism; fructose bisphophatase | ++ | −/++++ |
| Z48054 | PXR1 | Metabolism; peroxisome biogenesis | ++ | +/++ |
| D84145 | WS-3a | Dynatin 6 | ++ | +/++ |
| D14661 | KIAA0105a | Transcription; WT1-associating protein | ++ | +/++ |
| X77548 | NCOA4 | Transcription; nuclear receptor coactivator | ++ | +/++ |
| M90696 | CTSS | Cysteine protease | ++ | +/++ |
| D11086 | IL2RG | Cytokine receptor | ++ | +/++ |
| U70426 | RGS16 | Signaling; GTPase activating protein | ++ | +/+++ |
| X14850 | H2AX | Histone; required for antibody maturation | ++ | +/+++ |
| M29927 | OAT | Metabolism; ornithine aminotransferase | ++ | +/+++ |
| S74017 | NFE2L2 | Transcription | ++ | +/+++ |
| HT4604 | GYG | Metabolism; glycogen biogenesis | ++ | +/+++ |
| M55531 | SLC2A5 | Metabolism; fructose transporter | ++ | +/++++ |
| M60750 | H2BFL | Histone; nucleosome | ++ | +/++++ |
| L19437 | TALDO1 | Metabolism; transaldolase | ++ | ++/+++ |
| M10901 | NR3C1 | Transcription; glucocorticoid receptor | ++ | ++/+++ |
| L41887 | SFRS7 | mRNA splicing factor | ++ | ++/+++ |
| M34423 | GLB1 | Metabolism; galactosidase | ++ | ++/++++ |
| X15414 | AKR1B1 | Metabolism; aldose reductase | +++ | +/++++ |
| J04456 | LGALS1 | Signaling; inhibits CD45 phosphatase | +++ | +/++++ |
| X92493 | PIP5K1B | Signaling; kinase | +++ | +/++++ |
| U51478 | ATP1B3 | Na+, K+transporter | +++ | ++/++++ |
| X91257 | SARS | Seryl-tRNA synthetase | +++ | ++/++++ |
| D30655 | EIF4A2 | Translation initiation | +++ | ++/++++ |
| D31887 | KIAA0062a | Unknown | +++ | ++/++++ |
| X04106 | CAPN4 | Cysteine protease; calcium dependent | +++ | ++/++++ |
| D87442 | NCSTNa | Nicastrin | +++ | ++/++++ |
| L76191 | IRAK1 | Signaling; cytokine receptor kinase | +++ | +++/++++ |
| HT1428 | HBB | Hemoglobin | ++++ | −/++++ |
| U44975 | COPEB | Oncogene; transcription factor | ++++ | −/++++ |
| X55733 | EIF4B | Translation initiation | ++++ | +/++++ |
| L09604 | PLP2 | Signaling; colonic epithelium differentiation | ++++ | +/++++ |
| HT1614 | PPP1CA | Signaling; phosphatase | ++++ | +++/++++ |
| L26247 | SUI1a | Translation initiation; probable | ++++ | +++/++++ |
Please see Table 2 note.
The range of QGE levels for genes with variable expression in MM are given as lowest level/highest level.