Ability of LPSs from wild and recombinant strains ofE coli to induce rapid shock
LPS . | Dose, mg/kg . | Incidence . | Shock score . | Mortality . |
---|---|---|---|---|
E coliK-12 | 2 | 0/4 | 0 | 0/4 |
4 | 5/9 | 1 | 0/9 | |
E coliO8* | 0.5 | 0/4 | 0 | 0/4 |
1 | 4/4 | 2 | 0/4 | |
2 | 4/4 | 2-4 | 0/4 | |
E coliO9* | 0.25 | 1/4 | 0-1 | 0/4 |
0.5 | 4/4 | 2-3 | 0/4 | |
1 | 4/4 | 3-4 | 0/4 | |
2 | 4/4 | 4 | 3/4 | |
E coli rO8* | 0.5 | 4/4 | 1 | 0/4 |
1 | 4/4 | 2-4 | 0/4 | |
2 | 4/4 | 4 | 4/4 | |
E coli rO9* | 0.25 | 4/4 | 1 | 0/4 |
0.5 | 4/4 | 3-4 | 1/4 | |
1 | 4/4 | 4 | 3/4 | |
E coliO111 | 4 | 0/5 | 0 | 0/5 |
KlebsiellaO3-S* | 0.5 | 4/4 | 4 | 3/4 |
KlebsiellaO3-R | 4 | 0/4 | 0 | 0/4 |
LPS . | Dose, mg/kg . | Incidence . | Shock score . | Mortality . |
---|---|---|---|---|
E coliK-12 | 2 | 0/4 | 0 | 0/4 |
4 | 5/9 | 1 | 0/9 | |
E coliO8* | 0.5 | 0/4 | 0 | 0/4 |
1 | 4/4 | 2 | 0/4 | |
2 | 4/4 | 2-4 | 0/4 | |
E coliO9* | 0.25 | 1/4 | 0-1 | 0/4 |
0.5 | 4/4 | 2-3 | 0/4 | |
1 | 4/4 | 3-4 | 0/4 | |
2 | 4/4 | 4 | 3/4 | |
E coli rO8* | 0.5 | 4/4 | 1 | 0/4 |
1 | 4/4 | 2-4 | 0/4 | |
2 | 4/4 | 4 | 4/4 | |
E coli rO9* | 0.25 | 4/4 | 1 | 0/4 |
0.5 | 4/4 | 3-4 | 1/4 | |
1 | 4/4 | 4 | 3/4 | |
E coliO111 | 4 | 0/5 | 0 | 0/5 |
KlebsiellaO3-S* | 0.5 | 4/4 | 4 | 3/4 |
KlebsiellaO3-R | 4 | 0/4 | 0 | 0/4 |
Data for LPSs from E coli O111 andKlebsiella O3-S and R are from our previous report.5
The O regions of the LPSs of these bacteria are composed of MHP.