Relationship between maximum DLI dose and GVHD in 71 sibling RIC allografts
| Maximum dose CD3+ cells received . | Median day after transplantation (range) . | AGVHD . | AGVHD2+ . | Chronic GVHD5-150 . |
|---|---|---|---|---|
| Less than 5 × 106/kg | 125 (76-412) | 4/13 | 3/13 | 3/11 |
| 1 × 107/kg | 179 (75-1111) | 9/25 | 8/25 | 7/21 |
| 2-6 × 107/kg | 210 (99-494) | 9/25 | 7/25 | 8/24 |
| 0.8-3 × 108/kg | 116 (77-455) | 1/8 | 1/8 | 2/7 |
| Maximum dose CD3+ cells received . | Median day after transplantation (range) . | AGVHD . | AGVHD2+ . | Chronic GVHD5-150 . |
|---|---|---|---|---|
| Less than 5 × 106/kg | 125 (76-412) | 4/13 | 3/13 | 3/11 |
| 1 × 107/kg | 179 (75-1111) | 9/25 | 8/25 | 7/21 |
| 2-6 × 107/kg | 210 (99-494) | 9/25 | 7/25 | 8/24 |
| 0.8-3 × 108/kg | 116 (77-455) | 1/8 | 1/8 | 2/7 |
AGVHD indicates acute GVHD, any grade; AGVHD2+, acute GVHD grades II to IV.
Eight patients did not survive 100 days after the DLI.