DLIs
Characteristic . | No. . |
---|---|
Disease-specific therapy prior to DLIs | 9 |
First infusion (n = 81) | |
Days after transplantation | 149 (61-1008) |
Median cell dose, per kg recipient weight | 5 × 106 (105-108) |
Second infusion (n = 34) | |
Days after transplantation | 210 (90-1029) |
Median cell dose, per kg recipient weight | 1 × 107 (3 × 106-108) |
Median days between first and second DLI and range | 45 (8-554) |
Third infusion (n = 15) | |
Days after transplantation | 303 (105-1111) |
Median cell dose, per kg recipient weight | 5 × 107 (107-108) |
Median days between second and third DLI and range | 42 (14-119) |
Cytokines given after DLI | 0 |
Donor reaccessed/stored DLI3-150 | 54/26 |
GVHD prior to first DLI | 14 |
On immunosuppression at time of first DLI | 10 |
Indication | |
Progressive/persistent disease | 51 |
MC | 18 |
Preemptive | 10 |
Other | 2 |
Pre-DLI chimerism | |
All donor | 20 |
MC | 54 |
ND/NK | 6 |
All recipient | 1 |
Characteristic . | No. . |
---|---|
Disease-specific therapy prior to DLIs | 9 |
First infusion (n = 81) | |
Days after transplantation | 149 (61-1008) |
Median cell dose, per kg recipient weight | 5 × 106 (105-108) |
Second infusion (n = 34) | |
Days after transplantation | 210 (90-1029) |
Median cell dose, per kg recipient weight | 1 × 107 (3 × 106-108) |
Median days between first and second DLI and range | 45 (8-554) |
Third infusion (n = 15) | |
Days after transplantation | 303 (105-1111) |
Median cell dose, per kg recipient weight | 5 × 107 (107-108) |
Median days between second and third DLI and range | 42 (14-119) |
Cytokines given after DLI | 0 |
Donor reaccessed/stored DLI3-150 | 54/26 |
GVHD prior to first DLI | 14 |
On immunosuppression at time of first DLI | 10 |
Indication | |
Progressive/persistent disease | 51 |
MC | 18 |
Preemptive | 10 |
Other | 2 |
Pre-DLI chimerism | |
All donor | 20 |
MC | 54 |
ND/NK | 6 |
All recipient | 1 |
ND/NK indicates not done/not known.
Source of DLI not known in one patient.