Effect of activation of hIL-3 (M) Rα, hβc compared to wild-type hIL-3 Rα, hβcon expression of differentiation markers
| Receptor transfect . | Sca-1 . | Gr-1 . | Mac-1 . |
|---|---|---|---|
| Wild-type hIL-3 Rα, hβc | 1.04 ± 0.08 | 1.12 ± 0.1 | 1.19 ± 0.11 |
| hIL-3 (M) Rα, hβc | 1.28 ± 0.19 | 2.75 ± 1.2 | 3.24 ± 1.54 |
| Receptor transfect . | Sca-1 . | Gr-1 . | Mac-1 . |
|---|---|---|---|
| Wild-type hIL-3 Rα, hβc | 1.04 ± 0.08 | 1.12 ± 0.1 | 1.19 ± 0.11 |
| hIL-3 (M) Rα, hβc | 1.28 ± 0.19 | 2.75 ± 1.2 | 3.24 ± 1.54 |
Changes in differentiation marker expression are shown as a fold increase in fluorescence intensity compared to levels expressed on control cells cultured in rmIL-3 (10 ng/mL), which are assigned a value of 1. Data are the mean of at least 3 experiments ± SEM.