PF-4 inhibits FGF2-induced ACE proliferation
| . | Cell no. × 10−3/well . | % of control . |
|---|---|---|
| Control | 50.7 ± 10.1 | 100.0 ± 20.0 |
| FGF2 | 131.5 ± 27.3 | 259.1 ± 53.8 |
| FGF2 + PF-4 | 47.6 ± 11.3 | 93.8 ± 22.4 |
| . | Cell no. × 10−3/well . | % of control . |
|---|---|---|
| Control | 50.7 ± 10.1 | 100.0 ± 20.0 |
| FGF2 | 131.5 ± 27.3 | 259.1 ± 53.8 |
| FGF2 + PF-4 | 47.6 ± 11.3 | 93.8 ± 22.4 |
ACE cells, seeded at 35 000 cells/dish, were cultured in serum-deprived medium with or without FGF2 (10 ng/mL), in the presence or absence of PF-4 (10 μg/mL). After 7 days of culture, cells were counted. Data are the means (SEM) of counts for 3 dishes.