Cytogenetic findings and IPSS classification at diagnosis
| . | MDS-Eos, n = 33, % . | MDS-Bas, n = 32, % . | MDS−/−, n = 209, % . | P . |
|---|---|---|---|---|
| Cytogenetics | < .0001 | |||
| Good | 18 | 19 | 60 | |
| Intermediate | 15 | 28 | 19 | |
| Poor | 67 | 53 | 21 | |
| IPSS | .0012 | |||
| Low | 3 | 3 | 13 | |
| Intermediate-1 | 30 | 22 | 47 | |
| Intermediate-2 | 40 | 37.5 | 26 | |
| High | 27 | 37.5 | 14 |
| . | MDS-Eos, n = 33, % . | MDS-Bas, n = 32, % . | MDS−/−, n = 209, % . | P . |
|---|---|---|---|---|
| Cytogenetics | < .0001 | |||
| Good | 18 | 19 | 60 | |
| Intermediate | 15 | 28 | 19 | |
| Poor | 67 | 53 | 21 | |
| IPSS | .0012 | |||
| Low | 3 | 3 | 13 | |
| Intermediate-1 | 30 | 22 | 47 | |
| Intermediate-2 | 40 | 37.5 | 26 | |
| High | 27 | 37.5 | 14 |
Successful cytogenetic analysis at diagnosis was obtained from 264 patients. Coexistence of bone marrow eosinophilia and basophilia was observed in 11 patients. Good prognosis karyotypes were normal, −Y, del(5q), and del(20q). Poor prognosis karyotypes were complex or chromosome 7 abnormalities. Other abnormalities were classified as intermediate karyotypes.8