Clinical and hematologic characteristics at diagnosis of the MDS-Eos, MDS-Bas, and MDS−/− patients
. | MDS-Eos, n = 36 . | MDS-Bas, n = 34 . | MDS−/−, n = 229 . | P . |
---|---|---|---|---|
FAB (%) | < .05 | |||
RA | 10 (28) | 2 (6) | 82 (36) | |
RARS | 0 (0) | 2 (6) | 13 (6) | |
RAEB | 12 (33) | 19 (56) | 68 (30) | |
RAEBt | 10 (28) | 8 (23) | 47 (20) | |
CMML | 4 (11) | 3 (9) | 19 (8) | |
Sex | NS | |||
Male | 29 | 26 | 150 | |
Female | 7 | 8 | 79 | |
Median age, y (range) | 68 (23-87) | 64.5 (25-87) | 68 (15-93) | NS |
Peripheral blood (range) | ||||
Hb, g/dL | 6.9 (3.1-11.8) | 7.4 (4.2-11.4) | 8.0 (3.2-13.6)* | < .05 |
PMN, × 109/L | 1.9 (0.1-33.3) | 2.0 (0.2-33.3) | 1.3 (0.1-39.2) | NS |
Eos, × 109/L | 0.15 (0-2.1)† | 0.05 (0-2.1)‡ | 0.02 (0-1.2) | < .01 |
Bas, × 109/L | 0.02 (0-0.36) | 0.06 (0-0.84)1-153 | 0.01 (0-0.89) | < .01 |
Plt, × 109/L | 84 (12-1400) | 84 (1.0-1400) | 60 (0.5-1240) | NS |
. | MDS-Eos, n = 36 . | MDS-Bas, n = 34 . | MDS−/−, n = 229 . | P . |
---|---|---|---|---|
FAB (%) | < .05 | |||
RA | 10 (28) | 2 (6) | 82 (36) | |
RARS | 0 (0) | 2 (6) | 13 (6) | |
RAEB | 12 (33) | 19 (56) | 68 (30) | |
RAEBt | 10 (28) | 8 (23) | 47 (20) | |
CMML | 4 (11) | 3 (9) | 19 (8) | |
Sex | NS | |||
Male | 29 | 26 | 150 | |
Female | 7 | 8 | 79 | |
Median age, y (range) | 68 (23-87) | 64.5 (25-87) | 68 (15-93) | NS |
Peripheral blood (range) | ||||
Hb, g/dL | 6.9 (3.1-11.8) | 7.4 (4.2-11.4) | 8.0 (3.2-13.6)* | < .05 |
PMN, × 109/L | 1.9 (0.1-33.3) | 2.0 (0.2-33.3) | 1.3 (0.1-39.2) | NS |
Eos, × 109/L | 0.15 (0-2.1)† | 0.05 (0-2.1)‡ | 0.02 (0-1.2) | < .01 |
Bas, × 109/L | 0.02 (0-0.36) | 0.06 (0-0.84)1-153 | 0.01 (0-0.89) | < .01 |
Plt, × 109/L | 84 (12-1400) | 84 (1.0-1400) | 60 (0.5-1240) | NS |
NS indicates not significant; PMN, polymorphonuclear neutrophil; and Plt, platelet.
Hb concentration of the MDS−/− group is significantly higher than that of the MDS-Eos group.
Circulating eosinophil counts were significantly higher in MDS-Eos compared with those in MDS-Bas and MDS−/−.
Circulating eosinophil counts were significantly higher in MDS-Bas compared with those in MDS−/−.
Circulating basophil counts were significantly higher in MDS-Bas compared with those in MDS-Eos and MDS−/−.