Numbers and frequencies of hematopoietic stem cells (HSCs)
| . | Number . | Frequency of HSCs . |
|---|---|---|
| Mice | ||
| Abkowitz et al1 | 11 200-22 400 HSCs/mouse* | 4-8 HSCs/105 BM cells |
| Coggle et al2 | 36 000-125 000 HSCs/mouse† | 7-14 HSCs/105 BM cells |
| Humans | ||
| Abkowitz et al1 | 11 200-22 400 HSCs/person | 0.7-1.5 HSCs/108 BM cells‡ |
| (mean) | (16 800 HSCs/person) | |
| Gordon et al3 | 36 000-125 000 HSCs/person | 2.4-8.3 HSCs/108 BM cells‡ |
| (mean) | (81 000 HSCs/person) | |
| Elephants8 | ||
| Abkowitz et al1 | 11 200-22 400 HSCs/elephant | 0.8-1.5 HSCs/1010 BM cells‡ |
| (Mean) | (16 800 HSCs/elephant) | |
| Gordon et al3 | 36 000-125 000 HSCs/elephant | 2.4-8.3 HSCs/1010 BM cells1-153 |
| (Mean) | (81 000 HSCs/elephant) |
| . | Number . | Frequency of HSCs . |
|---|---|---|
| Mice | ||
| Abkowitz et al1 | 11 200-22 400 HSCs/mouse* | 4-8 HSCs/105 BM cells |
| Coggle et al2 | 36 000-125 000 HSCs/mouse† | 7-14 HSCs/105 BM cells |
| Humans | ||
| Abkowitz et al1 | 11 200-22 400 HSCs/person | 0.7-1.5 HSCs/108 BM cells‡ |
| (mean) | (16 800 HSCs/person) | |
| Gordon et al3 | 36 000-125 000 HSCs/person | 2.4-8.3 HSCs/108 BM cells‡ |
| (mean) | (81 000 HSCs/person) | |
| Elephants8 | ||
| Abkowitz et al1 | 11 200-22 400 HSCs/elephant | 0.8-1.5 HSCs/1010 BM cells‡ |
| (Mean) | (16 800 HSCs/elephant) | |
| Gordon et al3 | 36 000-125 000 HSCs/elephant | 2.4-8.3 HSCs/1010 BM cells1-153 |
| (Mean) | (81 000 HSCs/elephant) |
Calculated from frequency by × 2.8 × 108 BM cells/mouse.
Calculated from frequency by × 5-9 × 108 BM cells/mouse.
Calculated from number by ÷ 1.5 × 1012 BM cells/person.
Calculated from number by ÷ 1.5 × 1014 BM cells per elephant, under assumption that elephants have the same number of stem cells as mice and humans. See Table 2.