Table 6. Clinical data of patients with... | American Society of Hematology

Table 6.

Clinical data of patients with CLL detecting 0 to 7 clones

Patient sera	Detected clones	Rai stage	Hypogamma-globulinemia	Autoimmune phenomena	Prior therapy	CD38, % expression on CLL cells	IgH mutation	Cytogenetics
1	0	I	Low	No	No	2	Yes	13q del
2	0	II	Low	No	Yes	n.d.	Yes	Normal
3	0	II	Low	Yes	Yes	85	Yes	Normal
4	1	I	Normal	No	No	17	Yes	13q del
5	1	IV	Normal	No	Yes	83	No	Normal
6	1	I	Low	No	No	12	Yes	Normal
7	1	II	Low	Yes	No	15	No	+12
8	1	I	Low	No	No	4	Yes	Normal
9	1	II	Normal	Yes	Yes	39	Yes	11q del
10	1	II	Low	Yes	Yes	14	No	Normal
11	2	II	Normal	Yes	Yes	79	Yes	Normal
12	2	IV	Low	No	Yes	86	Yes	Normal
13	2	IV	Normal	No	No	n.d.	Yes	n.d.
14	3	I	Normal	No	No	10	Yes	Normal
15	3	I	Normal	No	No	0	No	13q del
16	4	II	Normal	No	No	16	Yes	+12, +18
17	7	II	Normal	No	No	7	Yes	13q del

Patient sera	Detected clones	Rai stage	Hypogamma-globulinemia	Autoimmune phenomena	Prior therapy	CD38, % expression on CLL cells	IgH mutation	Cytogenetics
1	0	I	Low	No	No	2	Yes	13q del
2	0	II	Low	No	Yes	n.d.	Yes	Normal
3	0	II	Low	Yes	Yes	85	Yes	Normal
4	1	I	Normal	No	No	17	Yes	13q del
5	1	IV	Normal	No	Yes	83	No	Normal
6	1	I	Low	No	No	12	Yes	Normal
7	1	II	Low	Yes	No	15	No	+12
8	1	I	Low	No	No	4	Yes	Normal
9	1	II	Normal	Yes	Yes	39	Yes	11q del
10	1	II	Low	Yes	Yes	14	No	Normal
11	2	II	Normal	Yes	Yes	79	Yes	Normal
12	2	IV	Low	No	Yes	86	Yes	Normal
13	2	IV	Normal	No	No	n.d.	Yes	n.d.
14	3	I	Normal	No	No	10	Yes	Normal
15	3	I	Normal	No	No	0	No	13q del
16	4	II	Normal	No	No	16	Yes	+12, +18
17	7	II	Normal	No	No	7	Yes	13q del

Stage, serum Ig, autoimmune phenomena, therapy prior to serum harvest, CD38 expression level on CLL cells, presence of somatic hypermutation in the Ig rearrangement, and cytogenetic abnormalities are shown.

n.d. indicates not done.

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