Infectious Diseases Society of America and United States Public Health Service grading system for ranking recommendations4
| Category/grade . | Definition . |
|---|---|
| Strength of recommendation | |
| A | Good evidence to support a recommendation for use |
| B | Moderate evidence to support a recommendation for use |
| C | Poor evidence to support a recommendation |
| D | Moderate evidence to support a recommendation against use |
| E | Good evidence to support a recommendation against use |
| Quality of evidence | |
| I | Evidence from ≥ 1 properly randomized, controlled trial |
| II | Evidence from ≥ 1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from > 1 center); from multiple-time series; or from dramatic results from uncontrolled experiments |
| III | Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees |
| Category/grade . | Definition . |
|---|---|
| Strength of recommendation | |
| A | Good evidence to support a recommendation for use |
| B | Moderate evidence to support a recommendation for use |
| C | Poor evidence to support a recommendation |
| D | Moderate evidence to support a recommendation against use |
| E | Good evidence to support a recommendation against use |
| Quality of evidence | |
| I | Evidence from ≥ 1 properly randomized, controlled trial |
| II | Evidence from ≥ 1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from > 1 center); from multiple-time series; or from dramatic results from uncontrolled experiments |
| III | Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees |