Phenotypic analysis of the bone marrow, spleen, and thymus of Fanca knockout mice
| Source . | Phenotype . | Fanca+/+ . | Fanca−/− . |
|---|---|---|---|
| BM | B220 | 21.4 ± 2.2 | 23.6 ± 2.8 |
| GR1 | 69.8 ± 10.6 | 59.8 ± 4.5 | |
| MAC | 60.4 ± 10.9 | 58.1 ± 2.9 | |
| CD3 | 1.89 ± 0.38 | 3.46 ± 1.36 | |
| TER-119 | 17.2 ± 1.1 | 15.5 ± 5.1 | |
| Lin−Sca-1+ | 0.74 ± 0.13 | 0.77 ± 0.16 | |
| Lin− c-kit+Sca-1+ | 0.45 ± 0.18 | 0.47 ± 0.16 | |
| Spleen | B220 | 47.1 ± 5.2 | 50.5 ± 2.5 |
| GR1 | 38.5 ± 11.6 | 34.2 ± 2.4 | |
| MAC | 15.1 ± 8.1 | 4.86 ± 0.28 | |
| CD3 | 20.8 ± 4.9 | 34.3 ± 5.0 | |
| TER-119 | 6.6 ± 1.1 | 4.5 ± 0.3 | |
| Thymus | CD3 | 36.3 ± 14.6 | 34.7 ± 12.3 |
| CD4+CD8− | 4.4 ± 1.4 | 3.2 ± 0.98 | |
| CD8+CD4− | 33.4 ± 10.7 | 27.9 ± 11.2 | |
| CD4+CD8+ | 55.3 ± 9.3 | 65.6 ± 10.3 | |
| CD4−CD8− | 5.3 ± 0.7 | 3.1 ± 0.63 |
| Source . | Phenotype . | Fanca+/+ . | Fanca−/− . |
|---|---|---|---|
| BM | B220 | 21.4 ± 2.2 | 23.6 ± 2.8 |
| GR1 | 69.8 ± 10.6 | 59.8 ± 4.5 | |
| MAC | 60.4 ± 10.9 | 58.1 ± 2.9 | |
| CD3 | 1.89 ± 0.38 | 3.46 ± 1.36 | |
| TER-119 | 17.2 ± 1.1 | 15.5 ± 5.1 | |
| Lin−Sca-1+ | 0.74 ± 0.13 | 0.77 ± 0.16 | |
| Lin− c-kit+Sca-1+ | 0.45 ± 0.18 | 0.47 ± 0.16 | |
| Spleen | B220 | 47.1 ± 5.2 | 50.5 ± 2.5 |
| GR1 | 38.5 ± 11.6 | 34.2 ± 2.4 | |
| MAC | 15.1 ± 8.1 | 4.86 ± 0.28 | |
| CD3 | 20.8 ± 4.9 | 34.3 ± 5.0 | |
| TER-119 | 6.6 ± 1.1 | 4.5 ± 0.3 | |
| Thymus | CD3 | 36.3 ± 14.6 | 34.7 ± 12.3 |
| CD4+CD8− | 4.4 ± 1.4 | 3.2 ± 0.98 | |
| CD8+CD4− | 33.4 ± 10.7 | 27.9 ± 11.2 | |
| CD4+CD8+ | 55.3 ± 9.3 | 65.6 ± 10.3 | |
| CD4−CD8− | 5.3 ± 0.7 | 3.1 ± 0.63 |
Data are given as mean ± SEM of at least 4 different animals at age 8 to 10 weeks.