Survival at the latest follow-up with regard to age in 113 patients with HLH treated according to the HLH-94 protocol
| Age at onset of therapy . | All patients (n = 113) . | Familial cases (n = 25) . | BMT patients (n = 65) . | Patients alive and off therapy without BMT (n = 20) . |
|---|---|---|---|---|
| 0 to younger than 3 mo | 12 of 30 (40%) | 6 of 13 (46%) | 11 of 21 (52%) | |
| 3 mo to younger than 12 mo | 15 of 34 (44%) | 2 of 4 (50%) | 14 of 22 (64%) | 1 of 1 |
| 12 mo to younger than 24 mo | 19 of 25 (76%) | 3 of 4 (75%) | 10 of 14 (71%) | 8 of 8 |
| 24 mo or older | 17 of 24 (71%) | 2 of 4 (50%) | 5 of 8 (62%) | 11 of 11 |
| Totals | 63 of 113 (56%) | 13 of 25 (52%) | 40 of 65 (62%) | 20 of 20 |
| Mean age | 19 mo | 13 mo | 13 mo | 47 mo |
| Age range | 0-145 mo | 0-82 mo | 0-84 mo | 10-145 mo |
| Age at onset of therapy . | All patients (n = 113) . | Familial cases (n = 25) . | BMT patients (n = 65) . | Patients alive and off therapy without BMT (n = 20) . |
|---|---|---|---|---|
| 0 to younger than 3 mo | 12 of 30 (40%) | 6 of 13 (46%) | 11 of 21 (52%) | |
| 3 mo to younger than 12 mo | 15 of 34 (44%) | 2 of 4 (50%) | 14 of 22 (64%) | 1 of 1 |
| 12 mo to younger than 24 mo | 19 of 25 (76%) | 3 of 4 (75%) | 10 of 14 (71%) | 8 of 8 |
| 24 mo or older | 17 of 24 (71%) | 2 of 4 (50%) | 5 of 8 (62%) | 11 of 11 |
| Totals | 63 of 113 (56%) | 13 of 25 (52%) | 40 of 65 (62%) | 20 of 20 |
| Mean age | 19 mo | 13 mo | 13 mo | 47 mo |
| Age range | 0-145 mo | 0-82 mo | 0-84 mo | 10-145 mo |