The effect of maintenance chemotherapy by risk group
Risk . | No. of maintenance chemotherapy agents . | n . | Relapse, % (range) . | DFS, % (range) . | OS, % (range) . |
---|---|---|---|---|---|
Standard | 0-1 | 7 | 29 (9-92) | 43 (6-80) | 36 (0-75) |
2-3 | 29 | 17 (7-44) | 79 (62-96) | 83 (67-99) | |
P | .07 | .002 | .0007 | ||
Intermediate | 0-1 | 12 | 50 (28-88) | 25 (5-50) | 33 (7-60) |
2-3 | 16 | 45 (26-79) | 55 (29-80) | 52 (25-78) | |
P | .09 | .008 | .03 | ||
High | 0-1 | 7 | 86 (63-100) | 14 (0-40) | 14 (0-40) |
2-3 | 6 | 83 (58-100) | 0 | 25 (0-65) | |
P | .75 | .75 | .45 |
Risk . | No. of maintenance chemotherapy agents . | n . | Relapse, % (range) . | DFS, % (range) . | OS, % (range) . |
---|---|---|---|---|---|
Standard | 0-1 | 7 | 29 (9-92) | 43 (6-80) | 36 (0-75) |
2-3 | 29 | 17 (7-44) | 79 (62-96) | 83 (67-99) | |
P | .07 | .002 | .0007 | ||
Intermediate | 0-1 | 12 | 50 (28-88) | 25 (5-50) | 33 (7-60) |
2-3 | 16 | 45 (26-79) | 55 (29-80) | 52 (25-78) | |
P | .09 | .008 | .03 | ||
High | 0-1 | 7 | 86 (63-100) | 14 (0-40) | 14 (0-40) |
2-3 | 6 | 83 (58-100) | 0 | 25 (0-65) | |
P | .75 | .75 | .45 |
The figures represent 10-year cumulative incidence of relapse and the 10-year probabilities of DFS and OS.