Table 2. Chimerism and TCR Vβ repertoire... | American Society of Hematology

Table 2.

Chimerism and TCR Vβ repertoire reconstitution

Day	Chimerism^*		No. bands per Vβ family, mean ± SD
Day	Mixed	Complete donor	CD4⁺ CD45RA⁺	CD4⁺CD45RO⁺	CD8⁺CD45RA⁺	CD8⁺ CD45RO⁺
0-100	2/10^†	8 of 10	—	4.7 ± 2.3	—	2.9 ± 1.7
101-200	5/10^†	5 of 10	—	4.8 ± 2.5	—	3.4 ± 2
201-300	4/9^†	5 of 9	6.5 ± 2.4	5.7 ± 2.3	6 ± 2	4.3 ± 2.2
> 300	3/6^†	3 of 6	6.6 ± 2.2	5.2 ± 2.4	6.6 ± 1.8	5.3 ± 2.4^‡
Control	—	—	6.5 ± 1.3	6.5 ± 1.4	5.5 ± 1.6	4.6 ± 1.7^‡

Day	Chimerism^*		No. bands per Vβ family, mean ± SD
Day	Mixed	Complete donor	CD4⁺ CD45RA⁺	CD4⁺CD45RO⁺	CD8⁺CD45RA⁺	CD8⁺ CD45RO⁺
0-100	2/10^†	8 of 10	—	4.7 ± 2.3	—	2.9 ± 1.7
101-200	5/10^†	5 of 10	—	4.8 ± 2.5	—	3.4 ± 2
201-300	4/9^†	5 of 9	6.5 ± 2.4	5.7 ± 2.3	6 ± 2	4.3 ± 2.2
> 300	3/6^†	3 of 6	6.6 ± 2.2	5.2 ± 2.4	6.6 ± 1.8	5.3 ± 2.4^‡
Control	—	—	6.5 ± 1.3	6.5 ± 1.4	5.5 ± 1.6	4.6 ± 1.7^‡

Determined by PCR of variable number tandem repeats in whole blood samples as previously described.22

Median percentage of recipient cells in whole blood was 2.5%.

Skewing within the CD8⁺CD45RO⁺ compartment could be observed in transplant recipients beyond day 300 and in healthy controls.