Virologic evaluation after CTL infusion
Patient no. . | Virologic findings . | Before CTL infusion . | After CTL infusion3-150 . |
---|---|---|---|
1 | EA mRNA | Positive | Negative |
EBV-antigenemia | Positive | Negative | |
Anti-VCA | >1:640 | 1:160 | |
Anti-EBNA | Negative | N/A | |
2 | Anti-VCA | 1:640 | 1:80 |
Anti-EBNA | Negative | 1:20 | |
3 | Anti-VCA | 1:640 | 1:80 |
Anti-EBNA | 1:5 | 1:5 | |
EBV-DNA | 97 | 0 | |
4 | Anti-VCA | 1:640 | 1:80 |
Anti-EBNA | Negative | 1:40 | |
5 | Anti-VCA | 1:1280 | 1:160 |
Anti-EBNA | Negative | 1:80 |
Patient no. . | Virologic findings . | Before CTL infusion . | After CTL infusion3-150 . |
---|---|---|---|
1 | EA mRNA | Positive | Negative |
EBV-antigenemia | Positive | Negative | |
Anti-VCA | >1:640 | 1:160 | |
Anti-EBNA | Negative | N/A | |
2 | Anti-VCA | 1:640 | 1:80 |
Anti-EBNA | Negative | 1:20 | |
3 | Anti-VCA | 1:640 | 1:80 |
Anti-EBNA | 1:5 | 1:5 | |
EBV-DNA | 97 | 0 | |
4 | Anti-VCA | 1:640 | 1:80 |
Anti-EBNA | Negative | 1:40 | |
5 | Anti-VCA | 1:1280 | 1:160 |
Anti-EBNA | Negative | 1:80 |
CTL indicates cytotoxic T lymphocytes; EA mRNA, early antigen messenger RNA; VCA, anti–viral capsid antigen (IgG); EBNA, anti-EBV nuclear antigen (IgG); and N/A, not available.
Evaluation performed 2 weeks after the adoptive transfer. Data were reconfirmed at the 4-week post-CTL infusion follow-up evaluation.