Significantly different immunophenotypes between low-risk MDS, high-risk MDS, and AL-MDS
| . | CD10 . | CD15 . | CD7 . | CD117 . | ||||
|---|---|---|---|---|---|---|---|---|
| Positive . | Negative . | Positive . | Negative . | Positive . | Negative . | Positive . | Negative . | |
| Low-risk MDS | ||||||||
| Number of cases (%)6-150 | 9 (39.1) | 23 | 21 (95.5) | 1 | 0 (0) | 23 | 8 (36.4) | 14 |
| Percent positive EBCs6-151 | ||||||||
| Median | 36 | 15 | 44 | 2 | N/A | 8 | 41 | 9 |
| Range | 29-72 | 8-19 | 24-82 | 2 | N/A | 1-18 | 22-85 | 1-19 |
| High-risk MDS | ||||||||
| Number of cases (%) | 10 (13.9) | 62 | 40 (56.3) | 31 | 29 (40.3) | 43 | 51 (71.8) | 20 |
| Percent positive EBCs | ||||||||
| Median | 36 | 7 | 41 | 10 | 35 | 9 | 58 | 11 |
| Range | 21-58 | 0-19 | 21-80 | 1-19 | 21-73 | 1-17 | 23-96 | 1-19 |
| AL-MDS | ||||||||
| Number of cases (%) | 3 (14.3) | 18 | 12 (57.1) | 9 | 11 (52.4) | 10 | 14 (66.7) | 7 |
| Percent positive EBCs | ||||||||
| Median | 22 | 8 | 40 | 10 | 40 | 6 | 64 | 2 |
| Range | 22-43 | 1-19 | 24-99 | 0-19 | 21-98 | 0-16 | 21-92 | 0-19 |
| . | CD10 . | CD15 . | CD7 . | CD117 . | ||||
|---|---|---|---|---|---|---|---|---|
| Positive . | Negative . | Positive . | Negative . | Positive . | Negative . | Positive . | Negative . | |
| Low-risk MDS | ||||||||
| Number of cases (%)6-150 | 9 (39.1) | 23 | 21 (95.5) | 1 | 0 (0) | 23 | 8 (36.4) | 14 |
| Percent positive EBCs6-151 | ||||||||
| Median | 36 | 15 | 44 | 2 | N/A | 8 | 41 | 9 |
| Range | 29-72 | 8-19 | 24-82 | 2 | N/A | 1-18 | 22-85 | 1-19 |
| High-risk MDS | ||||||||
| Number of cases (%) | 10 (13.9) | 62 | 40 (56.3) | 31 | 29 (40.3) | 43 | 51 (71.8) | 20 |
| Percent positive EBCs | ||||||||
| Median | 36 | 7 | 41 | 10 | 35 | 9 | 58 | 11 |
| Range | 21-58 | 0-19 | 21-80 | 1-19 | 21-73 | 1-17 | 23-96 | 1-19 |
| AL-MDS | ||||||||
| Number of cases (%) | 3 (14.3) | 18 | 12 (57.1) | 9 | 11 (52.4) | 10 | 14 (66.7) | 7 |
| Percent positive EBCs | ||||||||
| Median | 22 | 8 | 40 | 10 | 40 | 6 | 64 | 2 |
| Range | 22-43 | 1-19 | 24-99 | 0-19 | 21-98 | 0-16 | 21-92 | 0-19 |
Low-risk MDS includes RA and RARS. High-risk MDS includes CMML, RAEB, and RAEB-t.
N/A indicates not applicable.
Number of cases that were positive or negative for each antigen. The positive-case percentages are shown in parentheses and differ significantly between low-risk MDS, high-risk MDS, and AL-MDS (P values are .0225, .0029, .0003, and .0098 for CD10, CD15, CD7, and CD117, respectively).
The percentage of EBCs positive for each antigen (median and range).