Expression of lymphoid antigens on EBCs
| Disease . | CD2 . | CD3 . | CD4 . | CD5 . | CD7 . | CD8 . | CD10 . | CD19 . | CD20 . | CD16 . | CD56 . | CD25 . | Immature B cells4-150 . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RA | 0/19 | 0/18 | 10/18 (44, 25-67) | 0/18 | 0/19 | 0/18 | 7/19 (39, 29-72) | 0/18 | 0/18 | 0/19 | 2/19 (49, 41-56) | 1/18 (28) | 2/17 |
| RARS | 0/4 | 0/4 | 1/4 (35) | 0/4 | 0/4 | 0/4 | 2/4 (31, 31-31) | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 |
| CMML | 0/5 | 0/5 | 2/5 (53, 25-80) | 0/5 | 2/5 (24, 21-27) | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 | 0/3 |
| RAEB | 1/36 (81) | 0/36 | 18/36 (32, 24-83) | 0/36 | 11/36 (27, 23-73) | 0/36 | 6/36 (36, 29-58) | 0/36 | 0/36 | 0/36 | 8/36 (61, 21-77) | 6/35 (41, 27-61) | 1/26 |
| RAEB-t | 0/31 | 0/30 | 13/30 (39, 23-84) | 0/30 | 16/31 (41, 21-64) | 0/30 | 4/31 (35, 21-49) | 0/30 | 0/30 | 0/31 | 15/31 (37, 25-81) | 6/28 (28, 24-68) | 0/16 |
| AL-MDS | 1/21 (96) | 0/21 | 10/21 (40, 23-94) | 1/21 (26) | 11/21 (40, 21-98) | 0/21 | 3/21 (22, 22-43) | 0/21 | 0/21 | 0/21 | 6/21 (60, 23-99) | 5/21 (55, 23-76) | 0/13 |
| Disease . | CD2 . | CD3 . | CD4 . | CD5 . | CD7 . | CD8 . | CD10 . | CD19 . | CD20 . | CD16 . | CD56 . | CD25 . | Immature B cells4-150 . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RA | 0/19 | 0/18 | 10/18 (44, 25-67) | 0/18 | 0/19 | 0/18 | 7/19 (39, 29-72) | 0/18 | 0/18 | 0/19 | 2/19 (49, 41-56) | 1/18 (28) | 2/17 |
| RARS | 0/4 | 0/4 | 1/4 (35) | 0/4 | 0/4 | 0/4 | 2/4 (31, 31-31) | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 |
| CMML | 0/5 | 0/5 | 2/5 (53, 25-80) | 0/5 | 2/5 (24, 21-27) | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 | 0/3 |
| RAEB | 1/36 (81) | 0/36 | 18/36 (32, 24-83) | 0/36 | 11/36 (27, 23-73) | 0/36 | 6/36 (36, 29-58) | 0/36 | 0/36 | 0/36 | 8/36 (61, 21-77) | 6/35 (41, 27-61) | 1/26 |
| RAEB-t | 0/31 | 0/30 | 13/30 (39, 23-84) | 0/30 | 16/31 (41, 21-64) | 0/30 | 4/31 (35, 21-49) | 0/30 | 0/30 | 0/31 | 15/31 (37, 25-81) | 6/28 (28, 24-68) | 0/16 |
| AL-MDS | 1/21 (96) | 0/21 | 10/21 (40, 23-94) | 1/21 (26) | 11/21 (40, 21-98) | 0/21 | 3/21 (22, 22-43) | 0/21 | 0/21 | 0/21 | 6/21 (60, 23-99) | 5/21 (55, 23-76) | 0/13 |
Data in the upper row for each disease subtype are the number of cases: positive cases/total cases analyzed. Data in parentheses are the percentages of blasts expressing each antigen in the positive cases (median, range).
Cases whose EBC phenotype was analyzed for BM samples and who had CD45lowCD34+CD10+CD19+CD20±and/or CD45lowCD34−CD10+CD19+CD20+B-cell precursors. For the 3 cases who had B-cell precursors, the data for each antigen in Tables 3 and 4 are those of gated blasts other than the B-cell precursors.