Table 3.

Criteria used for risk-stratifying patients with PV and ET according to the conventional 2-tiered score and the revised IPSET-thrombosis for ET

Risk categoryPVET
2-tiered score2-tiered scoreRevised IPSET
Very low — — No thrombosis history, age ≤60 y and JAK2-unmutated 
Low ≤60 y of age, and no history of thrombosis ≤60 y of age, and no history of thrombosis No thrombosis history, age ≤60 y and JAK2V617F-mutated 
Intermediate — As low risk, but with cardiovascular risk factor No thrombosis history, age >60 y and JAK2-unmutated 
High >60 y of age and/or with history of thrombosis >60 y of age and/or with history of thrombosis Thrombosis history or age >60 y with JAK2V617 mutation 
Risk categoryPVET
2-tiered score2-tiered scoreRevised IPSET
Very low — — No thrombosis history, age ≤60 y and JAK2-unmutated 
Low ≤60 y of age, and no history of thrombosis ≤60 y of age, and no history of thrombosis No thrombosis history, age ≤60 y and JAK2V617F-mutated 
Intermediate — As low risk, but with cardiovascular risk factor No thrombosis history, age >60 y and JAK2-unmutated 
High >60 y of age and/or with history of thrombosis >60 y of age and/or with history of thrombosis Thrombosis history or age >60 y with JAK2V617 mutation 

—, not applicable.

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