Indications for transfusion in pregnant women with SCD30,43
| Indication . | Comment . |
|---|---|
| Women with previous serious medical, obstetric, or fetal complications | Consider prophylactic RCE |
| Women who are on transfusion regimen before pregnancy for primary or secondary stroke prevention or for the prevention of severe disease complications | Continue prepregnancy transfusion program |
| Twin pregnancies | Consider prophylactic RCE as high rate of complications in twin pregnancies |
| Acute anemia | Simple transfusion if Hb <7 g/dL or >2 g/dL below baseline |
| Acute chest syndrome, acute stroke, or other acute complication | Emergency RCE followed by prophylactic transfusion thereafter |
| Repeated pain crises during pregnancy | Emergency RCE followed by prophylactic transfusion thereafter |
| Indication . | Comment . |
|---|---|
| Women with previous serious medical, obstetric, or fetal complications | Consider prophylactic RCE |
| Women who are on transfusion regimen before pregnancy for primary or secondary stroke prevention or for the prevention of severe disease complications | Continue prepregnancy transfusion program |
| Twin pregnancies | Consider prophylactic RCE as high rate of complications in twin pregnancies |
| Acute anemia | Simple transfusion if Hb <7 g/dL or >2 g/dL below baseline |
| Acute chest syndrome, acute stroke, or other acute complication | Emergency RCE followed by prophylactic transfusion thereafter |
| Repeated pain crises during pregnancy | Emergency RCE followed by prophylactic transfusion thereafter |